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CHICK:NTRK2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) NTRK2 (synonyms: TRKB)
Protein Name(s) BDNF/NT-3 growth factors receptor

Neurotrophic tyrosine kinase receptor type 2 TrkB tyrosine kinase Trk-B

External Links
UniProt Q91987
EMBL X77251
X77252
X74109
PIR S59938
S59939
RefSeq NP_990562.1
UniGene Gga.681
ProteinModelPortal Q91987
SMR Q91987
MEROPS I43.001
PaxDb Q91987
Ensembl ENSGALT00000020568
GeneID 396157
KEGG gga:396157
CTD 4915
eggNOG COG0515
GeneTree ENSGT00760000118818
HOGENOM HOG000264255
HOVERGEN HBG056735
InParanoid Q91987
KO K04360
OMA CEIMWIK
PhylomeDB Q91987
BRENDA 2.7.10.1
Reactome REACT_211519
NextBio 20816213
PRO PR:Q91987
Proteomes UP000000539
GO GO:0005829
GO:0010008
GO:0005887
GO:0097481
GO:0045211
GO:0043235
GO:0043195
GO:0005524
GO:0048403
GO:0060175
GO:0043121
GO:0042803
GO:0031547
GO:0035584
GO:0021954
GO:0021987
GO:0007623
GO:0007631
GO:0014047
GO:0007612
GO:0060291
GO:0042490
GO:2000811
GO:0043524
GO:0007528
GO:0030182
GO:0001764
GO:0048709
GO:0048935
GO:0050772
GO:0008284
GO:0010628
GO:0043410
GO:0010976
GO:0014068
GO:0046777
GO:0051896
GO:0032314
GO:0046548
GO:0001570
Gene3D 2.60.40.10
InterPro IPR000483
IPR007110
IPR013783
IPR013098
IPR003598
IPR011009
IPR001611
IPR000372
IPR000719
IPR017441
IPR001245
IPR020455
IPR008266
IPR020635
IPR020777
IPR002011
Pfam PF07679
PF13855
PF07714
PRINTS PR01939
PR01941
PR00109
SMART SM00408
SM00082
SM00013
SM00219
SUPFAM SSF56112
PROSITE PS50835
PS51450
PS00107
PS50011
PS00109
PS00239

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

C

Seeded From UniProt

complete

involved_in

GO:0048672

positive regulation of collateral sprouting

PMID:19036963[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

part_of:(GO:0031547)

Seeded From UniProt

complete

involved_in

GO:0048668

collateral sprouting

PMID:19036963[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(CL:0009004)

Seeded From UniProt

complete

enables

GO:0005004

GPI-linked ephrin receptor activity

PMID:19036963[1]

ECO:0000314

direct assay evidence used in manual assertion

F

part_of:(GO:0031547)

Seeded From UniProt

complete

enables

GO:0005244

voltage-gated ion channel activity

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:1903859

regulation of dendrite extension

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

enables

GO:0060175

brain-derived neurotrophic factor-activated receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

F

Seeded From UniProt

complete

enables

GO:0060175

brain-derived neurotrophic factor-activated receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

F

Seeded From UniProt

complete

enables

GO:0060175

brain-derived neurotrophic factor-activated receptor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16620

F

Seeded From UniProt

complete

involved_in

GO:0050772

positive regulation of axonogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

enables

GO:0048403

brain-derived neurotrophic factor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

F

Seeded From UniProt

complete

enables

GO:0048403

brain-derived neurotrophic factor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

F

Seeded From UniProt

complete

involved_in

GO:0046777

protein autophosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

involved_in

GO:0043524

negative regulation of neuron apoptotic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

involved_in

GO:0043410

positive regulation of MAPK cascade

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

enables

GO:0043121

neurotrophin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

F

Seeded From UniProt

complete

enables

GO:0043121

neurotrophin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

F

Seeded From UniProt

complete

enables

GO:0043121

neurotrophin binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16620

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

F

Seeded From UniProt

complete

involved_in

GO:0043087

regulation of GTPase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0031547

brain-derived neurotrophic factor receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0031547

brain-derived neurotrophic factor receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

involved_in

GO:0031547

brain-derived neurotrophic factor receptor signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16620

P

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0021987

cerebral cortex development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0021954

central nervous system neuron development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

involved_in

GO:0010976

positive regulation of neuron projection development

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:0008284

positive regulation of cell population proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

P

Seeded From UniProt

complete

involved_in

GO:0007612

learning

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q63604

C

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q16620

C

Seeded From UniProt

complete

involved_in

GO:0001764

neuron migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P15209

P

Seeded From UniProt

complete

involved_in

GO:1990416

cellular response to brain-derived neurotrophic factor stimulus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000699897
RGD:3213

P

Seeded From UniProt

complete

involved_in

GO:1990090

cellular response to nerve growth factor stimulus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97383
PANTHER:PTN001230900
RGD:3213
RGD:620144
UniProtKB:P04629

P

Seeded From UniProt

complete

involved_in

GO:0099551

trans-synaptic signaling by neuropeptide, modulating synaptic transmission

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
PANTHER:PTN000699897

P

Seeded From UniProt

complete

NOT|involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002400475
UniProtKB:P04629

P

Seeded From UniProt

complete

enables

GO:0060175

brain-derived neurotrophic factor-activated receptor activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
PANTHER:PTN000699897
RGD:3213
UniProtKB:Q16620

F

Seeded From UniProt

complete

involved_in

GO:0051896

regulation of protein kinase B signaling

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
PANTHER:PTN000698829

P

Seeded From UniProt

complete

enables

GO:0048403

brain-derived neurotrophic factor binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
PANTHER:PTN000699897
RGD:3213

F

Seeded From UniProt

complete

part_of

GO:0043679

axon terminus

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000699897
RGD:3213

C

Seeded From UniProt

complete

involved_in

GO:0043410

positive regulation of MAPK cascade

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002400475
RGD:3213
UniProtKB:Q16288

P

Seeded From UniProt

complete

involved_in

GO:0043408

regulation of MAPK cascade

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002400475
RGD:3213
UniProtKB:Q16288

P

Seeded From UniProt

complete

part_of

GO:0043235

receptor complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015380
FB:FBgn0024245
FB:FBgn0033791
PANTHER:PTN002356460
UniProtKB:A6QR62
UniProtKB:O15146
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P11362
UniProtKB:P14616
UniProtKB:P17948
UniProtKB:P21860
UniProtKB:P35916
UniProtKB:Q01973
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q16288
UniProtKB:Q16620

C

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000699897
RGD:3213

C

Seeded From UniProt

complete

enables

GO:0043121

neurotrophin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
PANTHER:PTN001230900
RGD:3213
UniProtKB:Q16620

F

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97383
PANTHER:PTN001230900
RGD:3213
RGD:620144

C

Seeded From UniProt

complete

part_of

GO:0014069

postsynaptic density

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
PANTHER:PTN000699897
RGD:3213

C

Seeded From UniProt

complete

involved_in

GO:0014068

positive regulation of phosphatidylinositol 3-kinase signaling

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002400475
RGD:3213

P

Seeded From UniProt

complete

involved_in

GO:0010976

positive regulation of neuron projection development

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97384
MGI:MGI:97385
PANTHER:PTN002400475
RGD:3213
RGD:3214
UniProtKB:Q91987

P

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97383
MGI:MGI:97384
MGI:MGI:97385
PANTHER:PTN002400475
RGD:3213
RGD:3214
RGD:620144
UniProtKB:P04629
UniProtKB:Q91987
ZFIN:ZDB-GENE-010126-3

P

Seeded From UniProt

complete

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003366
FB:FBgn0003731
FB:FBgn0003733
FB:FBgn0283499
MGI:MGI:104757
MGI:MGI:109378
MGI:MGI:1096337
MGI:MGI:1339758
MGI:MGI:1345277
MGI:MGI:95276
MGI:MGI:95278
MGI:MGI:95294
MGI:MGI:95522
MGI:MGI:95523
MGI:MGI:95524
MGI:MGI:95525
MGI:MGI:95558
MGI:MGI:95561
MGI:MGI:96575
MGI:MGI:96677
MGI:MGI:96683
MGI:MGI:96969
MGI:MGI:97384
MGI:MGI:97530
MGI:MGI:97531
MGI:MGI:97902
MGI:MGI:98277
MGI:MGI:99216
MGI:MGI:99611
MGI:MGI:99612
MGI:MGI:99654
PANTHER:PTN002356460
RGD:2543
RGD:2611
RGD:2612
RGD:2621
RGD:2869
RGD:2917
RGD:2965
RGD:3082
RGD:3213
RGD:3214
RGD:3284
RGD:3285
RGD:620144
RGD:620714
RGD:620831
RGD:621737
RGD:69323
UniProtKB:A6QR62
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P09619
UniProtKB:P10721
UniProtKB:P11362
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35916
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:P54764
UniProtKB:Q02763
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q15375
UniProtKB:Q16288
UniProtKB:Q16620
UniProtKB:Q16832
UniProtKB:Q5JZY3
UniProtKB:Q91987
WB:WBGene00001184
WB:WBGene00006868
ZFIN:ZDB-GENE-020503-1
ZFIN:ZDB-GENE-020503-2
ZFIN:ZDB-GENE-060503-14
ZFIN:ZDB-GENE-070713-2
ZFIN:ZDB-GENE-980526-255
ZFIN:ZDB-GENE-980526-326
ZFIN:ZDB-GENE-990415-62

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003366
FB:FBgn0003731
FB:FBgn0003733
FB:FBgn0011829
FB:FBgn0015380
FB:FBgn0032006
FB:FBgn0283499
MGI:MGI:103581
MGI:MGI:104771
MGI:MGI:109378
MGI:MGI:98277
MGI:MGI:99611
PANTHER:PTN002356460
RGD:1560587
RGD:3213
RGD:3214
RGD:70957
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07949
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:Q02763
UniProtKB:Q16620
UniProtKB:Q9UM73
WB:WBGene00000289
WB:WBGene00000898

C

Seeded From UniProt

complete

enables

GO:0005030

neurotrophin receptor activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001230900
RGD:3213
UniProtKB:Q16288

F

Seeded From UniProt

complete

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003733
FB:FBgn0040505
FB:FBgn0283499
MGI:MGI:109378
MGI:MGI:1339758
MGI:MGI:1345277
MGI:MGI:95276
MGI:MGI:95294
MGI:MGI:95522
MGI:MGI:95524
MGI:MGI:95558
MGI:MGI:95561
MGI:MGI:96677
MGI:MGI:96683
MGI:MGI:96969
MGI:MGI:97384
MGI:MGI:97530
MGI:MGI:97902
MGI:MGI:98277
MGI:MGI:99611
MGI:MGI:99612
MGI:MGI:99654
PANTHER:PTN002356460
RGD:2543
RGD:2611
RGD:2621
RGD:2869
RGD:2917
RGD:2965
RGD:3082
RGD:3213
RGD:3214
RGD:3284
RGD:3285
RGD:620144
RGD:620714
RGD:620831
RGD:621737
UniProtKB:P00533
UniProtKB:P04626
UniProtKB:P04629
UniProtKB:P06213
UniProtKB:P07333
UniProtKB:P07949
UniProtKB:P08069
UniProtKB:P09619
UniProtKB:P10721
UniProtKB:P11362
UniProtKB:P14616
UniProtKB:P16234
UniProtKB:P17948
UniProtKB:P21709
UniProtKB:P21802
UniProtKB:P22455
UniProtKB:P22607
UniProtKB:P29317
UniProtKB:P29320
UniProtKB:P35916
UniProtKB:P35968
UniProtKB:P54753
UniProtKB:P54760
UniProtKB:P54762
UniProtKB:Q08345
UniProtKB:Q15303
UniProtKB:Q16620
UniProtKB:Q16832
UniProtKB:Q5JZY3
UniProtKB:Q91987
UniProtKB:Q9UM73
WB:WBGene00000289
WB:WBGene00006868
WB:WBGene00020504
ZFIN:ZDB-GENE-980526-255

F

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004714

P

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004713

P

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004714

P

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004713

P

Seeded From UniProt

complete

involved_in

GO:0018108

peptidyl-tyrosine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004714

P

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005244

P

Seeded From UniProt

complete

involved_in

GO:0038179

neurotrophin signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005030

P

Seeded From UniProt

complete

involved_in

GO:0038179

neurotrophin signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005030

P

Seeded From UniProt

complete

involved_in

GO:0048013

ephrin receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005004

P

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR008266

F

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020635

F

Seeded From UniProt

complete

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002011
InterPro:IPR020455
InterPro:IPR020777

F

Seeded From UniProt

complete

enables

GO:0005030

neurotrophin receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020455

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR002011
InterPro:IPR017441
InterPro:IPR020777

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020455
InterPro:IPR020777

C

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR001245
InterPro:IPR002011
InterPro:IPR008266
InterPro:IPR020455
InterPro:IPR020635
InterPro:IPR020777

P

Seeded From UniProt

complete

involved_in

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002011
InterPro:IPR020455
InterPro:IPR020777

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002011

C

Seeded From UniProt

complete

enables

GO:0004714

transmembrane receptor protein tyrosine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.10.1

F

Seeded From UniProt

complete

enables

GO:0005244

voltage-gated ion channel activity

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:1903859

regulation of dendrite extension

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005244

P

Seeded From UniProt

complete

enables

GO:0005244

voltage-gated ion channel activity

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:1903859

regulation of dendrite extension

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005244

P

Seeded From UniProt

complete

enables

GO:0005244

voltage-gated ion channel activity

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

F

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:1903859

regulation of dendrite extension

PMID:23035107[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(UBERON:0002830)

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005244

P

Seeded From UniProt

complete

enables

GO:0004713

protein tyrosine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0829

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005768

endosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0967

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0279

C

Seeded From UniProt

complete

part_of

GO:0010008

endosome membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0100

C

Seeded From UniProt

complete

part_of

GO:0030425

dendrite

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0283

C

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0198

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Marler, KJ et al. (2008) A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis. J. Neurosci. 28 12700-12 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Schecterson, LC et al. (2012) TrkB downregulation is required for dendrite retraction in developing neurons of chicken nucleus magnocellularis. J. Neurosci. 32 14000-9 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page