GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
CHICK:NTRK2
Contents
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030425 |
dendrite |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030424 |
axon |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048672 |
positive regulation of collateral sprouting |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
part_of:(GO:0031547) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048668 |
collateral sprouting |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
occurs_in:(CL:0009004) |
Seeded From UniProt |
complete | ||
enables |
GO:0005004 |
GPI-linked ephrin receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
part_of:(GO:0031547) |
Seeded From UniProt |
complete | ||
enables |
GO:0005244 |
voltage-gated ion channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903859 |
regulation of dendrite extension |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
enables |
GO:0060175 |
brain-derived neurotrophic factor-activated receptor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0060175 |
brain-derived neurotrophic factor-activated receptor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0060175 |
brain-derived neurotrophic factor-activated receptor activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050772 |
positive regulation of axonogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0048403 |
brain-derived neurotrophic factor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0048403 |
brain-derived neurotrophic factor binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046777 |
protein autophosphorylation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043524 |
negative regulation of neuron apoptotic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0043121 |
neurotrophin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0043121 |
neurotrophin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0043121 |
neurotrophin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043087 |
regulation of GTPase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0031547 |
brain-derived neurotrophic factor receptor signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0031547 |
brain-derived neurotrophic factor receptor signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0031547 |
brain-derived neurotrophic factor receptor signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030182 |
neuron differentiation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0021987 |
cerebral cortex development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0021954 |
central nervous system neuron development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010976 |
positive regulation of neuron projection development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010628 |
positive regulation of gene expression |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007612 |
learning |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001764 |
neuron migration |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1990416 |
cellular response to brain-derived neurotrophic factor stimulus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000699897 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1990090 |
cellular response to nerve growth factor stimulus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97383 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0099551 |
trans-synaptic signaling by neuropeptide, modulating synaptic transmission |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
P |
Seeded From UniProt |
complete | ||
NOT|involved_in |
GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002400475 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0060175 |
brain-derived neurotrophic factor-activated receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051896 |
regulation of protein kinase B signaling |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0048403 |
brain-derived neurotrophic factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0043679 |
axon terminus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000699897 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002400475 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043408 |
regulation of MAPK cascade |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002400475 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043235 |
receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0015380 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043197 |
dendritic spine |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000699897 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0043121 |
neurotrophin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0030424 |
axon |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97383 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0014069 |
postsynaptic density |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase signaling |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002400475 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010976 |
positive regulation of neuron projection development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97384 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007399 |
nervous system development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:97383 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003366 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003366 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005030 |
neurotrophin receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001230900 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003733 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004714 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004713 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004714 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004713 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0018108 |
peptidyl-tyrosine phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004714 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005244 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0038179 |
neurotrophin signaling pathway |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005030 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0038179 |
neurotrophin signaling pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005030 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0048013 |
ephrin receptor signaling pathway |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005004 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004713 |
protein tyrosine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005030 |
neurotrophin receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000719 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000719 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004714 |
transmembrane receptor protein tyrosine kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005244 |
voltage-gated ion channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903859 |
regulation of dendrite extension |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005244 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005244 |
voltage-gated ion channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903859 |
regulation of dendrite extension |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005244 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005244 |
voltage-gated ion channel activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903859 |
regulation of dendrite extension |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
occurs_in:(UBERON:0002830) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005244 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0004713 |
protein tyrosine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007399 |
nervous system development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030424 |
axon |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0010008 |
endosome membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030425 |
dendrite |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Marler, KJ et al. (2008) A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis. J. Neurosci. 28 12700-12 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Schecterson, LC et al. (2012) TrkB downregulation is required for dendrite retraction in developing neurons of chicken nucleus magnocellularis. J. Neurosci. 32 14000-9 PubMed GONUTS page
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
b
c
- GO:1990090 ! cellular response to nerve growth factor stimulus
- GO:1990416 ! cellular response to brain-derived neurotrophic factor stimulus
- GO:0030154 ! cell differentiation
- GO:0042995 ! cell projection
- GO:0007169 ! cell surface receptor protein tyrosine kinase signaling pathway
- GO:0021954 ! central nervous system neuron development
- GO:0021987 ! cerebral cortex development
- Chordata
- Coelurosauria
- GO:0048668 ! collateral sprouting
- Craniata
- GO:0005737 ! cytoplasm
e
m
n
- GO:0043524 ! negative regulation of neuron apoptotic process
- Neognathae
- GO:0007399 ! nervous system development
- GO:0030182 ! neuron differentiation
- GO:0001764 ! neuron migration
- GO:0005030 ! neurotrophin receptor activity
- GO:0043121 ! neurotrophin binding
- GO:0038179 ! neurotrophin signaling pathway
- GO:0000166 ! nucleotide binding
p
- GO:0018108 ! peptidyl-tyrosine phosphorylation
- GO:0048471 ! perinuclear region of cytoplasm
- Phasianidae
- Phasianinae
- GO:0016310 ! phosphorylation
- GO:0005886 ! plasma membrane
- GO:0008284 ! positive regulation of cell population proliferation
- GO:0048672 ! positive regulation of collateral sprouting
- GO:0050772 ! positive regulation of axonogenesis
- GO:0043410 ! positive regulation of MAPK cascade
- GO:0010628 ! positive regulation of gene expression
- GO:0010976 ! positive regulation of neuron projection development
- GO:0070374 ! positive regulation of ERK1 and ERK2 cascade
- GO:0014069 ! postsynaptic density
- GO:0046777 ! protein autophosphorylation
- GO:0042803 ! protein homodimerization activity
- GO:0004672 ! protein kinase activity
- GO:0006468 ! protein phosphorylation
- GO:0004713 ! protein tyrosine kinase activity
r
t