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CHICK:MYL6

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) MYL6
Protein Name(s) Myosin light polypeptide 6

G2 catalytic LC17-GI LC17-NM Myosin light chain alkali smooth-muscle/non-muscle isoforms

External Links
UniProt P02607
EMBL M15645
M15646
PIR A28488
B28488
UniGene Gga.840
PDB 1BR1
1BR4
1I84
3DTP
3J04
PDBsum 1BR1
1BR4
1I84
3DTP
3J04
ProteinModelPortal P02607
SMR P02607
IntAct P02607
PRIDE P02607
HOVERGEN HBG012180
InParanoid P02607
PhylomeDB P02607
EvolutionaryTrace P02607
Proteomes UP000000539
GO GO:0042641
GO:0005829
GO:0016460
GO:0097513
GO:0030898
GO:0005509
GO:0008307
GO:0031032
GO:0006200
Gene3D 1.10.238.10
InterPro IPR011992
IPR002048
Pfam PF13405
PF13499
SMART SM00054
PROSITE PS50222

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0045159

myosin II binding

PMID:9147986[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P02612,UniProtKB:P35748

F

Seeded From UniProt

complete

enables

GO:0045159

myosin II binding

PMID:9147986[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P02612,UniProtKB:P10587

F

Seeded From UniProt

complete

enables

GO:0032036

myosin heavy chain binding

PMID:9741621[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P10587

F

Seeded From UniProt

complete

enables

GO:0043531

ADP binding

PMID:9741621[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005859

muscle myosin complex

PMID:9147986[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

PMID:9741621[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0030239

myofibril assembly

PMID:9147986[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0008307

structural constituent of muscle

PMID:9147986[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:9147986[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

PMID:9741621[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005859

muscle myosin complex

PMID:9741621[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0097513

myosin II filament

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

contributes_to

GO:0051015

actin filament binding

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0042641

actomyosin

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0031032

actomyosin structure organization

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

contributes_to

GO:0030898

actin-dependent ATPase activity

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0016460

myosin II complex

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

PMID:24072716[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0030898

actin-dependent ATPase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60662

F

Seeded From UniProt

complete

enables

GO:0008307

structural constituent of muscle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60662

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002048

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-NUL-421724

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016459

myosin complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0518

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Rovner, AS et al. (1997) An insert in the motor domain determines the functional properties of expressed smooth muscle myosin isoforms. J. Muscle Res. Cell. Motil. 18 103-10 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Dominguez, R et al. (1998) Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell 94 559-71 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Billington, N et al. (2013) Characterization of three full-length human nonmuscle myosin II paralogs. J. Biol. Chem. 288 33398-410 PubMed GONUTS page