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CHICK:MUC6

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) MUC6
Protein Name(s) Mucin-6

Ovomucin, beta-subunit

External Links
UniProt F1NBL0
EMBL AADN02030346
AB180913
UniGene Gga.20106
ProteinModelPortal F1NBL0
STRING 9031.ENSGALP00000032057
Allergome 2741
PRIDE F1NBL0
eggNOG NOG12793
HOGENOM HOG000170714
HOVERGEN HBG082885
InParanoid F1NBL0
OrthoDB EOG73V6J9
TreeFam TF300299
Proteomes UP000000539
GO GO:0005576
InterPro IPR030124
IPR002919
IPR014853
IPR001007
IPR001846
PANTHER PTHR11339:SF264
Pfam PF08742
PF01826
PF00094
SMART SM00832
SM00214
SM00216
SUPFAM SSF57567
PROSITE PS51233

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005615

extracellular space

PMID:5119791[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003823

antigen binding

PMID:15373418[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0051258

protein polymerization

PMID:2327958[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0099512

supramolecular fiber

PMID:2327958[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030308

negative regulation of cell growth

DOI:10.1021/jf9800615

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042632

cholesterol homeostasis

PMID:11942477[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0030299

intestinal cholesterol absorption

PMID:11942477[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0046790

virion binding

DOI:10.1021/jf970445f

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0046790

virion binding

DOI:10.1021/jf960753y

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0002281

macrophage activation involved in immune response

PMID:9404068[5]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:6749856[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030277

maintenance of gastrointestinal epithelium

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030124

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Robinson, DS & Monsey, JB (1971) Studies on the composition of egg-white ovomucin. Biochem. J. 121 537-47 PubMed GONUTS page
  2. Kobayashi, K et al. (2004) Glycopeptide derived from hen egg ovomucin has the ability to bind enterohemorrhagic Escherichia coli O157:H7. J. Agric. Food Chem. 52 5740-6 PubMed GONUTS page
  3. 3.0 3.1 Rabouille, C et al. (1990) The supramolecular organization of ovomucin. Biophysical and morphological studies. Biochem. J. 266 697-706 PubMed GONUTS page
  4. 4.0 4.1 Nagaoka, S et al. (2002) Egg ovomucin attenuates hypercholesterolemia in rats and inhibits cholesterol absorption in Caco-2 cells. Lipids 37 267-72 PubMed GONUTS page
  5. Tanizaki, H et al. (1997) Activation of macrophages by sulfated glycopeptides in ovomucin, yolk membrane, and chalazae in chicken eggs. Biosci. Biotechnol. Biochem. 61 1883-9 PubMed GONUTS page
  6. Meek, RL et al. (1982) The signal sequence of ovalbumin is located near the NH2 terminus. J. Biol. Chem. 257 12245-51 PubMed GONUTS page