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CHICK:KITH

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) TK1
Protein Name(s) Thymidine kinase, cytosolic
External Links
UniProt P04047
EMBL K02611
PIR A00608
RefSeq NP_990229.1
UniGene Gga.421
ProteinModelPortal P04047
SMR P04047
STRING 9031.ENSGALP00000011630
PaxDb P04047
Ensembl ENSGALT00000011644
GeneID 395719
KEGG gga:395719
CTD 7083
eggNOG COG1435
GeneTree ENSGT00390000011309
HOGENOM HOG000076390
HOVERGEN HBG006215
InParanoid P04047
KO K00857
OMA GMATHDK
OrthoDB EOG7MSMPX
PhylomeDB P04047
TreeFam TF314839
BRENDA 2.7.1.21
Reactome REACT_260165
NextBio 20815789
PRO PR:P04047
Proteomes UP000000539
GO GO:0005737
GO:0005524
GO:0042802
GO:0004797
GO:0008270
GO:0071897
GO:0051289
InterPro IPR027417
IPR001267
IPR020633
PANTHER PTHR11441
Pfam PF00265
PIRSF PIRSF035805
SUPFAM SSF52540
PROSITE PS00603

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0008270

zinc ion binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P04183

F

Seeded From UniProt

complete

involved_in

GO:0046104

thymidine metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000154158
RGD:621014

P

Seeded From UniProt

complete

involved_in

GO:0006259

DNA metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10994
PANTHER:PTN000154158

P

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10994
MGI:MGI:98763
PANTHER:PTN000154158
TAIR:locus:2077382
TAIR:locus:2178297
dictyBase:DDB_G0289179

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:23351158[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P04047

F

Seeded From UniProt

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

involved_in

GO:0009157

deoxyribonucleoside monophosphate biosynthetic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004797

P

Seeded From UniProt

complete

involved_in

GO:0051289

protein homotetramerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04183
ensembl:ENSP00000301634

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04183
ensembl:ENSP00000301634

F

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04183
ensembl:ENSP00000301634

F

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P04184
ensembl:ENSMUSP00000026661

F

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001267
InterPro:IPR020633

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001267
InterPro:IPR020633

F

Seeded From UniProt

complete

enables

GO:0004797

thymidine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.21

F

Seeded From UniProt

complete

involved_in

GO:0071897

DNA biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0237

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Mutahir, Z et al. (2013) Thymidine kinase 1 regulatory fine-tuning through tetramer formation. FEBS J. 280 1531-41 PubMed GONUTS page