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CHICK:IL18

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IL18
Protein Name(s) Interleukin-18

IL-18

External Links
UniProt Q8QFQ8
EMBL AJ276025
UniGene Gga.17593
ProteinModelPortal Q8QFQ8
PaxDb Q8QFQ8
eggNOG NOG77229
HOVERGEN HBG102119
InParanoid Q8QFQ8
PRO PR:Q8QFQ8
Proteomes UP000000539
GO GO:0005615
InterPro IPR008996
IPR015529
IPR000975
PANTHER PTHR11326
Pfam PF00340
PIRSF PIRSF015162
PRINTS PR01933
SUPFAM SSF50353

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0035710

CD4-positive, alpha-beta T cell activation

PMID:12902481[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050671

positive regulation of lymphocyte proliferation

PMID:12902481[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000492)

Seeded From UniProt

complete

involved_in

GO:1902715

positive regulation of interferon-gamma secretion

PMID:12902481[1]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(CL:0000492)

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

C

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

P

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000975

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Göbel, TW et al. (2003) IL-18 stimulates the proliferation and IFN-gamma release of CD4+ T cells in the chicken: conservation of a Th1-like system in a nonmammalian species. J. Immunol. 171 1809-15 PubMed GONUTS page