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CHICK:HS2ST

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) HS2ST1 (synonyms: HS2ST)
Protein Name(s) Heparan sulfate 2-O-sulfotransferase 1

cHS2ST

External Links
UniProt Q76KB1
EMBL AB093516
RefSeq NP_989812.1
UniGene Gga.9290
PDB 3F5F
4NDZ
PDBsum 3F5F
4NDZ
ProteinModelPortal Q76KB1
DIP DIP-48642N
STRING 9031.ENSGALP00000010096
PaxDb Q76KB1
GeneID 395140
KEGG gga:395140
CTD 9653
eggNOG NOG293591
HOGENOM HOG000220833
HOVERGEN HBG053202
InParanoid Q76KB1
KO K02513
PhylomeDB Q76KB1
TreeFam TF315238
EvolutionaryTrace Q76KB1
NextBio 20815232
PRO PR:Q76KB1
Proteomes UP000000539
GO GO:0000139
GO:0016021
GO:0008146
Gene3D 3.40.50.300
InterPro IPR007734
IPR027417
IPR005331
PANTHER PTHR12129
Pfam PF03567
SUPFAM SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0015015

heparan sulfate proteoglycan biosynthetic process, enzymatic modification

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000951108
WB:WBGene00002029

P

Seeded From UniProt

complete

involved_in

GO:0015014

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346049
PANTHER:PTN000951108

P

Seeded From UniProt

complete

enables

GO:0008146

sulfotransferase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003089
PANTHER:PTN000951070

F

Seeded From UniProt

complete

enables

GO:0004394

heparan sulfate 2-O-sulfotransferase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0024230
MGI:MGI:1346049
PANTHER:PTN000951108
WB:WBGene00002029

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:19022906[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q76KB1

F

Seeded From UniProt

complete

involved_in

GO:0060676

ureteric bud formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8R3H7
ensembl:ENSMUSP00000043066

P

Seeded From UniProt

complete

involved_in

GO:0030202

heparin metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8R3H7
ensembl:ENSMUSP00000043066

P

Seeded From UniProt

complete

involved_in

GO:0015014

heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8R3H7
ensembl:ENSMUSP00000043066

P

Seeded From UniProt

complete

enables

GO:0004394

heparan sulfate 2-O-sulfotransferase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8R3H7
ensembl:ENSMUSP00000043066

F

Seeded From UniProt

complete

enables

GO:0008146

sulfotransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005331
InterPro:IPR007734

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005331
InterPro:IPR007734

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Bethea, HN et al. (2008) Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 105 18724-9 PubMed GONUTS page