CHICK:HPRT

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	HPRT1 (synonyms: HPRT)
Protein Name(s)	Hypoxanthine-guanine phosphoribosyltransferase HGPRT HGPRTase
External Links
UniProt	Q9W719
EMBL	AJ132697
RefSeq	NP_990179.1
UniGene	Gga.3545
ProteinModelPortal	Q9W719
SMR	Q9W719
STRING	9031.ENSGALP00000031748
PaxDb	Q9W719
PRIDE	Q9W719
GeneID	395653
KEGG	gga:395653
CTD	3251
eggNOG	COG0634
HOGENOM	HOG000236521
HOVERGEN	HBG000242
InParanoid	Q9W719
KO	K00760
PhylomeDB	Q9W719
UniPathway	UPA00591
NextBio	20815725
PRO	PR:Q9W719
Proteomes	UP000000539
GO	GO:0005694 GO:0005737 GO:0052657 GO:0004422 GO:0000287 GO:0000166 GO:0042803 GO:0002060 GO:0046038 GO:0006178 GO:0046100 GO:0043103 GO:0046040 GO:0032264 GO:0045964 GO:0051289 GO:0006164 GO:0006166
Gene3D	3.40.50.2020
InterPro	IPR005904 IPR000836 IPR029057
Pfam	PF00156
SUPFAM	SSF53271
TIGRFAMs	TIGR01203
PROSITE	PS00103

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0004422	hypoxanthine phosphoribosyltransferase activity	PMID:3996588^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0002060	purine nucleobase binding	PMID:3996588^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0002057	guanine binding	PMID:3996588^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005694	chromosome	PMID:10198428^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0052657	guanine phosphoribosyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	F	Seeded From UniProt	complete
involved_in	GO:0051289	protein homotetramerization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0046100	hypoxanthine metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0046040	IMP metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0046038	GMP catabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0045964	positive regulation of dopamine metabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0043103	hypoxanthine salvage	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	F	Seeded From UniProt	complete
involved_in	GO:0006178	guanine salvage	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0006166	purine ribonucleoside salvage	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0006164	purine nucleotide biosynthetic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	C	Seeded From UniProt	complete
enables	GO:0004422	hypoxanthine phosphoribosyltransferase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	F	Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P00492	F	Seeded From UniProt	complete
involved_in	GO:0046100	hypoxanthine metabolic process	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96217 PANTHER:PTN000501530 RGD:2826 UniProtKB:F4IA25 UniProtKB:P00492	P	Seeded From UniProt	complete
involved_in	GO:0032264	IMP salvage	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG20098 PANTHER:PTN000501530	P	Seeded From UniProt	complete
involved_in	GO:0032263	GMP salvage	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG20098 PANTHER:PTN000501530	P	Seeded From UniProt	complete
involved_in	GO:0006178	guanine salvage	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96217 PANTHER:PTN000501530 UniProtKB:P00492 UniProtKB:Q9NRG1	P	Seeded From UniProt	complete
involved_in	GO:0006168	adenine salvage	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96217 PANTHER:PTN000501530	P	Seeded From UniProt	complete
involved_in	GO:0006166	purine ribonucleoside salvage	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96217 PANTHER:PTN000501530 UniProtKB:P00492 UniProtKB:Q8IJS1	P	Seeded From UniProt	complete
enables	GO:0004422	hypoxanthine phosphoribosyltransferase activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG20098 MGI:MGI:96217 PANTHER:PTN000501530 RGD:2826 UniProtKB:F4IA25 UniProtKB:P00492 UniProtKB:P9WHQ9 UniProtKB:Q8IJS1 UniProtKB:Q9NRG1 UniProtKB:Q9W719	F	Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG20098 PANTHER:PTN000501530 UniProtKB:P00492	F	Seeded From UniProt	complete
enables	GO:0004422	hypoxanthine phosphoribosyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005904	F	Seeded From UniProt	complete
involved_in	GO:0006166	purine ribonucleoside salvage	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005904	P	Seeded From UniProt	complete
involved_in	GO:0009116	nucleoside metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000836	P	Seeded From UniProt	complete
enables	GO:0052657	guanine phosphoribosyltransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.4.2.8	F	Seeded From UniProt	complete
enables	GO:0004422	hypoxanthine phosphoribosyltransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.4.2.8	F	Seeded From UniProt	complete
enables	GO:0004422	hypoxanthine phosphoribosyltransferase activity	PMID:3996588^[1]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0002060	purine nucleobase binding	PMID:3996588^[1]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0016757	transferase activity, transferring glycosyl groups	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0328	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
involved_in	GO:0006166	purine ribonucleoside salvage	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0660	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
involved_in	GO:0032264	IMP salvage	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00591	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Veres, G et al. (1985) Purification and characterisation of chicken brain hypoxanthine-guanine phosphoribosyltransferase. FEBS Lett. 184 299-303 PubMed GONUTS page
↑ Fukagawa, T et al. (1999) The chicken HPRT gene: a counter selectable marker for the DT40 cell line. Nucleic Acids Res. 27 1966-9 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:3996588-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Veres, G et al. (1985) Purification and characterisation of chicken brain hypoxanthine-guanine phosphoribosyltransferase. FEBS Lett. 184 299-303 PubMed GONUTS page

[PMID:10198428-2] Fukagawa, T et al. (1999) The chicken HPRT gene: a counter selectable marker for the DT40 cell line. Nucleic Acids Res. 27 1966-9 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:HPRT

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Annotations

Notes

References

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