CHICK:HEMH

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	FECH
Protein Name(s)	Ferrochelatase, mitochondrial Heme synthase Protoheme ferro-lyase
External Links
UniProt	O42479
EMBL	U68033
RefSeq	NP_989527.1
UniGene	Gga.166
ProteinModelPortal	O42479
SMR	O42479
STRING	9031.ENSGALP00000028757
PaxDb	O42479
GeneID	374020
KEGG	gga:374020
CTD	2235
eggNOG	COG0276
HOGENOM	HOG000060727
HOVERGEN	HBG051898
InParanoid	O42479
KO	K01772
PhylomeDB	O42479
BRENDA	4.99.1.1
Reactome	REACT_115611
SABIO-RK	O42479
UniPathway	UPA00252
NextBio	20813547
PRO	PR:O42479
Proteomes	UP000000539
GO	GO:0005743 GO:0005759 GO:0051537 GO:0004325 GO:0046872 GO:0006783 GO:0042168 GO:0044281
HAMAP	MF_00323
InterPro	IPR001015 IPR019772
PANTHER	PTHR11108
Pfam	PF00762
TIGRFAMs	TIGR00109
PROSITE	PS00534

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0006783	heme biosynthetic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10431 MGI:MGI:95513 PANTHER:PTN000121751 RGD:1307556 SGD:S000005702 TAIR:locus:2180642 UniProtKB:O04921 UniProtKB:P9WNE3 UniProtKB:Q8ID58	P		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000121752 RGD:1307556 TAIR:locus:2180642 UniProtKB:Q8ID58	C		Seeded From UniProt	complete
enables	GO:0004325	ferrochelatase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10431 FB:FBgn0266268 MGI:MGI:95513 PANTHER:PTN000121751 RGD:1307556 SGD:S000005702 TAIR:locus:2180642 UniProtKB:O04921 UniProtKB:P22830 UniProtKB:Q8ID58 ZFIN:ZDB-GENE-000928-1	F		Seeded From UniProt	complete
enables	GO:0004325	ferrochelatase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001015 InterPro:IPR019772	F		Seeded From UniProt	complete
involved_in	GO:0006783	heme biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001015 InterPro:IPR019772	P		Seeded From UniProt	complete
enables	GO:0004325	ferrochelatase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:4.99.1.1	F		Seeded From UniProt	complete
involved_in	GO:0006783	heme biosynthetic process	Reactome:R-GGA-421525	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005759	mitochondrial matrix	Reactome:R-GGA-421447	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005743	mitochondrial inner membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0999 UniProtKB-SubCell:SL-0168	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0051536	iron-sulfur cluster binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0411	F		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496	C		Seeded From UniProt	complete
involved_in	GO:0006779	porphyrin-containing compound biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0627	P		Seeded From UniProt	complete
enables	GO:0051537	2 iron, 2 sulfur cluster binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0001	F		Seeded From UniProt	complete
involved_in	GO:0006783	heme biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0350	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F		Seeded From UniProt	complete
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References

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