CHICK:HEM0

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ALAS2 (synonyms: ALASE)
Protein Name(s)	5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS-E 5-aminolevulinic acid synthase 2 Delta-ALA synthase 2 Delta-aminolevulinate synthase 2
External Links
UniProt	P18080
EMBL	M24367
PIR	A31452
ProteinModelPortal	P18080
HOVERGEN	HBG005954
InParanoid	P18080
PhylomeDB	P18080
Reactome	REACT_115611
UniPathway	UPA00251
Proteomes	UP000000539
GO	GO:0005829 GO:0005759 GO:0003870 GO:0030170 GO:0006783 GO:0042168 GO:0006782 GO:0044281
Gene3D	3.40.640.10 3.90.1150.10
InterPro	IPR010961 IPR001917 IPR004839 IPR015424 IPR015421 IPR015422
Pfam	PF00155
SUPFAM	SSF53383
TIGRFAMs	TIGR01821
PROSITE	PS00599

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015421 InterPro:IPR015422	F		Seeded From UniProt	complete
enables	GO:0003870	5-aminolevulinate synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010961	F		Seeded From UniProt	complete
involved_in	GO:0009058	biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004839	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001917	F		Seeded From UniProt	complete
enables	GO:0030170	pyridoxal phosphate binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004839 InterPro:IPR010961	F		Seeded From UniProt	complete
involved_in	GO:0033014	tetrapyrrole biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010961	P		Seeded From UniProt	complete
enables	GO:0003870	5-aminolevulinate synthase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.3.1.37	F		Seeded From UniProt	complete
involved_in	GO:0006783	heme biosynthetic process	Reactome:R-GGA-421525	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-GGA-421495 Reactome:R-GGA-421457	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005759	mitochondrial matrix	Reactome:R-GGA-421493 Reactome:R-GGA-421457	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0016746	transferase activity, transferring acyl groups	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0012	F		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496	C		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0006783	heme biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0350	P		Seeded From UniProt	complete
part_of	GO:0005759	mitochondrial matrix	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0170	C		Seeded From UniProt	complete
involved_in	GO:0006782	protoporphyrinogen IX biosynthetic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00251	P		Seeded From UniProt	complete
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