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CHICK:GLUC

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) GCG
Protein Name(s) Glucagon

Glicentin-related polypeptide GRPP Glucagon Glucagon-like peptide 1 GLP-1 Glucagon-like peptide 1(7-37) GLP-1(7-37) Glucagon-like peptide 1(7-36) GLP-1(7-36) Glucagon-like peptide 2 GLP-2

External Links
UniProt P68259
EMBL Y07539
S78477
PIR I51301
S09992
RefSeq NP_001177094.1
NP_990591.1
UniGene Gga.704
ProteinModelPortal P68259
SMR P68259
STRING 9031.ENSGALP00000018068
PaxDb P68259
Ensembl ENSGALT00000018090
ENSGALT00000033134
GeneID 396196
KEGG gga:396196
CTD 2641
eggNOG NOG42743
GeneTree ENSGT00390000005372
HOGENOM HOG000231876
HOVERGEN HBG003010
InParanoid P68259
KO K05259
OMA KMKSIYF
OrthoDB EOG7WMCM1
PhylomeDB P68259
TreeFam TF332333
Reactome REACT_284991
REACT_294203
REACT_294579
REACT_307426
REACT_338222
REACT_345262
NextBio 20816248
PRO PR:P68259
Proteomes UP000000539
GO GO:0005737
GO:0005615
GO:0031769
GO:0005179
GO:0007188
GO:0043066
GO:0032099
GO:1900118
GO:2001243
GO:0090280
GO:0030819
GO:0070374
GO:0035948
GO:0051571
GO:0035774
GO:0033138
GO:0010800
GO:0032092
GO:0045860
GO:0010737
GO:0042594
InterPro IPR015550
IPR000532
PANTHER PTHR11418:SF0
Pfam PF00123
PRINTS PR00275
SMART SM00070
PROSITE PS00260

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0032099

negative regulation of appetite

PMID:12633888[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008

P

Seeded From UniProt

complete

involved_in

GO:0035774

positive regulation of insulin secretion involved in cellular response to glucose stimulus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008

P

Seeded From UniProt

complete

enables

GO:0031769

glucagon receptor binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152008
RGD:2668

F

Seeded From UniProt

complete

involved_in

GO:0010737

protein kinase A signaling

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008

P

Seeded From UniProt

complete

involved_in

GO:0007188

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152008
RGD:2668

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95674
PANTHER:PTN000152008
RGD:2668

C

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000152008
RGD:2668
UniProtKB:P01272

F

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P01275
ensembl:ENSP00000387662

F

Seeded From UniProt

complete

involved_in

GO:1900118

negative regulation of execution phase of apoptosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0090280

positive regulation of calcium ion import

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0051571

positive regulation of histone H3-K4 methylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0050796

regulation of insulin secretion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0045860

positive regulation of protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0043066

negative regulation of apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0035948

positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0035774

positive regulation of insulin secretion involved in cellular response to glucose stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0033138

positive regulation of peptidyl-serine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0032092

positive regulation of protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0010800

positive regulation of peptidyl-threonine phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0010737

protein kinase A signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

involved_in

GO:0007189

adenylate cyclase-activating G protein-coupled receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55095
ensembl:ENSMUSP00000099794

C

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000532
InterPro:IPR015550

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000532

C

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0372

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Tachibana, T et al. (2003) Intracerebroventricular injection of vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibits feeding in chicks. Neurosci. Lett. 339 203-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page