CHICK:GCSP

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	GLDC
Protein Name(s)	Glycine dehydrogenase (decarboxylating), mitochondrial Glycine cleavage system P protein Glycine decarboxylase Glycine dehydrogenase (aminomethyl-transferring)
External Links
UniProt	P15505
EMBL	M64402 D90266 D90240
PIR	A39521
RefSeq	NP_989653.1
UniGene	Gga.3393
ProteinModelPortal	P15505
STRING	9031.ENSGALP00000037556
PaxDb	P15505
GeneID	374222
KEGG	gga:374222
CTD	2731
eggNOG	COG1003
HOGENOM	HOG000239369
HOVERGEN	HBG005820
InParanoid	P15505
KO	K00281
PhylomeDB	P15505
BioCyc	MetaCyc:MONOMER-12926
BRENDA	1.4.4.2
NextBio	20813724
PRO	PR:P15505
Proteomes	UP000000539
GO	GO:0005739 GO:0004375 GO:0016829 GO:0030170 GO:0006546
Gene3D	3.40.640.10
HAMAP	MF_00711
InterPro	IPR001597 IPR003437 IPR020580 IPR020581 IPR015424 IPR015421
PANTHER	PTHR11773
Pfam	PF01212 PF02347
SUPFAM	SSF53383
TIGRFAMs	TIGR00461

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0004375	glycine dehydrogenase (decarboxylating) activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P23378	F	Seeded From UniProt	complete
involved_in	GO:0006546	glycine catabolic process	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P23378	P	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P23378	C	Seeded From UniProt	complete
involved_in	GO:0036255	response to methylamine	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:1903442	response to lipoic acid	PMID:7440563^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:7440563^[2]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:1903442	response to lipoic acid	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0070280	pyridoxal binding	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0047960	glycine dehydrogenase activity	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0006546	glycine catabolic process	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:3426593^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:7440562^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0036255	response to methylamine	PMID:7440563^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0047960	glycine dehydrogenase activity	PMID:1993704^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0006546	glycine catabolic process	PMID:1993704^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0030170	pyridoxal phosphate binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000206531 RGD:1308660	F	Seeded From UniProt	complete
involved_in	GO:0019464	glycine decarboxylation via glycine cleavage system	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000206531 RGD:1308660 SGD:S000004801	P	Seeded From UniProt	complete
enables	GO:0016594	glycine binding	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000206531 RGD:1308660	F	Seeded From UniProt	complete
part_of	GO:0005960	glycine cleavage complex	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000206531 RGD:1308660	C	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000206533 RGD:1308660 TAIR:locus:2057464 UniProtKB:P15505 UniProtKB:P23378 UniProtKB:Q94B78	C	Seeded From UniProt	complete
enables	GO:0004375	glycine dehydrogenase (decarboxylating) activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG11810 PANTHER:PTN000206531 RGD:1308660 SGD:S000004801 UniProtKB:P23378	F	Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015421 InterPro:IPR015422	F	Seeded From UniProt	complete
enables	GO:0004375	glycine dehydrogenase (decarboxylating) activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003437 InterPro:IPR020581	F	Seeded From UniProt	complete
involved_in	GO:0006520	cellular amino acid metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001597	P	Seeded From UniProt	complete
involved_in	GO:0006544	glycine metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003437	P	Seeded From UniProt	complete
involved_in	GO:0006546	glycine catabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR020581	P	Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001597	F	Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003437 InterPro:IPR020581	P	Seeded From UniProt	complete
enables	GO:0004375	glycine dehydrogenase (decarboxylating) activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.4.4.2	F	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496 UniProtKB-SubCell:SL-0173	C	Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P	Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Hiraga, K & Kikuchi, G (1980) The mitochondrial glycine cleavage system. Purification and properties of glycine decarboxylase from chicken liver mitochondria. J. Biol. Chem. 255 11664-70 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Hiraga, K & Kikuchi, G (1980) The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier protein. J. Biol. Chem. 255 11671-6 PubMed GONUTS page
↑ Fujiwara, K et al. (1987) Amino acid sequence of the phosphopyridoxyl peptide from P-protein of the chicken liver glycine cleavage system. Biochem. Biophys. Res. Commun. 149 621-7 PubMed GONUTS page
↑ ^4.0 ^4.1 Kume, A et al. (1991) The glycine cleavage system. Molecular cloning of the chicken and human glycine decarboxylase cDNAs and some characteristics involved in the deduced protein structures. J. Biol. Chem. 266 3323-9 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:7440562-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Hiraga, K & Kikuchi, G (1980) The mitochondrial glycine cleavage system. Purification and properties of glycine decarboxylase from chicken liver mitochondria. J. Biol. Chem. 255 11664-70 PubMed GONUTS page

[PMID:7440563-2] 2.0 ^2.1 ^2.2 Hiraga, K & Kikuchi, G (1980) The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier protein. J. Biol. Chem. 255 11671-6 PubMed GONUTS page

[PMID:3426593-3] Fujiwara, K et al. (1987) Amino acid sequence of the phosphopyridoxyl peptide from P-protein of the chicken liver glycine cleavage system. Biochem. Biophys. Res. Commun. 149 621-7 PubMed GONUTS page

[PMID:1993704-4] 4.0 ^4.1 Kume, A et al. (1991) The glycine cleavage system. Molecular cloning of the chicken and human glycine decarboxylase cDNAs and some characteristics involved in the deduced protein structures. J. Biol. Chem. 266 3323-9 PubMed GONUTS page

[PMID:21873635-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 ^5.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:GCSP

Contents

Annotations

Notes

References

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