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CHICK:FST

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) FST
Protein Name(s) Follistatin

FS Activin-binding protein

External Links
UniProt Q90844
EMBL X87609
U34589
PIR S55369
RefSeq NP_990531.1
UniGene Gga.3615
ProteinModelPortal Q90844
SMR Q90844
STRING 9031.ENSGALP00000023997
MEROPS I01.966
PaxDb Q90844
Ensembl ENSGALT00000024043
GeneID 396119
KEGG gga:396119
CTD 10468
eggNOG NOG267610
GeneTree ENSGT00440000033501
HOGENOM HOG000261649
HOVERGEN HBG051666
InParanoid Q90844
KO K04661
OMA EAVCASD
PhylomeDB Q90844
Reactome REACT_348724
NextBio 20816177
PRO PR:Q90844
Proteomes UP000000539
GO GO:0005615
GO:0048185
GO:0002244
GO:0032926
GO:1902870
GO:1902864
GO:1902876
GO:1902873
GO:0010977
GO:1902867
GO:0000122
GO:0051798
GO:0046670
GO:1901390
InterPro IPR003645
IPR015369
IPR002350
IPR017878
Pfam PF09289
PF07648
SMART SM00274
SM00280
PROSITE PS51465
PS51364

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1902876

negative regulation of embryonic pattern specification

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1902867

negative regulation of retina development in camera-type eye

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:1902864

negative regulation of embryonic camera-type eye development

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046670

positive regulation of retinal cell programmed cell death

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0032926

negative regulation of activin receptor signaling pathway

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0000966)

Seeded From UniProt

complete

involved_in

GO:0010977

negative regulation of neuron projection development

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0001795)

Seeded From UniProt

complete

involved_in

GO:1902873

negative regulation of horizontal cell localization

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0001791)

Seeded From UniProt

complete

involved_in

GO:1902870

negative regulation of amacrine cell differentiation

PMID:16872597[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0001791)

Seeded From UniProt

complete

involved_in

GO:1901390

positive regulation of transforming growth factor beta activation

PMID:17549728[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0048185

activin binding

PMID:7576634[3]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:7576634[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0050840

extracellular matrix binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1891351
MGI:MGI:98373
PANTHER:PTN001015480

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0026562
MGI:MGI:98373
PANTHER:PTN001015480
RGD:3742
UniProtKB:Q08629
UniProtKB:Q90844
UniProtKB:Q9BQ16
WB:WBGene00003893

C

Seeded From UniProt

complete

enables

GO:0005518

collagen binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001015480
UniProtKB:P09486

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98373
PANTHER:PTN001015480
RGD:3742
UniProtKB:P09486
UniProtKB:Q08629
UniProtKB:Q92563
WB:WBGene00003893

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Moreira, EF & Adler, R (2006) Effects of follistatin overexpression on cell differentiation in the chick embryo retina. Dev. Biol. 298 272-84 PubMed GONUTS page
  2. van den Berg, G et al. (2007) Patterns of expression of the Follistatin and Follistatin-like1 genes during chicken heart development: a potential role in valvulogenesis and late heart muscle cell formation. Anat Rec (Hoboken) 290 783-7 PubMed GONUTS page
  3. 3.0 3.1 Darland, DC et al. (1995) Activin A and follistatin expression in developing targets of ciliary ganglion neurons suggests a role in regulating neurotransmitter phenotype. Neuron 15 857-66 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page