CHICK:D2X2H3

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	nlgn1 (ECO:0000313 with EMBL:ADB12631.1)
Protein Name(s)	Neuroligin 1 (ECO:0000313 with EMBL:ADB12631.1) Neuroligin 1 isoform A1A2B (ECO:0000313 with EMBL:ADW09014.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000040855)
External Links
UniProt	D2X2H3
EMBL	AADN03005857 GQ489204 GU574580
UniGene	Gga.10094 Gga.24245
Ensembl	ENSGALT00000044932
GeneTree	ENSGT00760000118946
OMA	KFVELIV
Proteomes	UP000000539
GO	GO:0016020 GO:0007155
Gene3D	3.40.50.1820
InterPro	IPR029058 IPR002018 IPR019819 IPR000460 IPR030022
PANTHER	PTHR11559:SF52
Pfam	PF00135
PRINTS	PR01090
SUPFAM	SSF53474
PROSITE	PS00941

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0097105	presynaptic membrane assembly	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 MGI:MGI:2681835 PANTHER:PTN000168538 RGD:621117 RGD:621118 RGD:621119 UniProtKB:Q8N0W4	P	Seeded From UniProt	complete
involved_in	GO:0097104	postsynaptic membrane assembly	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 MGI:MGI:2444609 MGI:MGI:2681835 PANTHER:PTN000168538	P	Seeded From UniProt	complete
involved_in	GO:0050804	modulation of chemical synaptic transmission	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 MGI:MGI:2444609 MGI:MGI:2681835 PANTHER:PTN000168538 RGD:621117	P	Seeded From UniProt	complete
involved_in	GO:0048488	synaptic vesicle endocytosis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0083963 PANTHER:PTN000168538	P	Seeded From UniProt	complete
part_of	GO:0045202	synapse	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 MGI:MGI:2681835 MGI:MGI:3775191 PANTHER:PTN000168538 RGD:621117 RGD:621119 WB:WBGene00006412	C	Seeded From UniProt	complete
enables	GO:0042043	neurexin family protein binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0031866 MGI:MGI:2179435 MGI:MGI:2681835 PANTHER:PTN000168538 RGD:621117 RGD:621119 UniProtKB:Q8N0W4	F	Seeded From UniProt	complete
enables	GO:0038023	signaling receptor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000168538 RGD:621117 RGD:621119	F	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 PANTHER:PTN000168538 RGD:621117 RGD:621118 RGD:621119 UniProtKB:Q8N0W4 UniProtKB:Q9NZ94	C	Seeded From UniProt	complete
involved_in	GO:0007158	neuron cell-cell adhesion	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 PANTHER:PTN000168538 RGD:621117 RGD:621118 RGD:621119	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2179435 PANTHER:PTN000168538 UniProtKB:Q8N0W4	C	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0097091	C	Seeded From UniProt	complete
part_of	GO:0098793	presynapse	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0048488	C	Seeded From UniProt	complete
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	P	Seeded From UniProt	complete
involved_in	GO:2000310	regulation of NMDA receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	P	Seeded From UniProt	complete
enables	GO:0097110	scaffold protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	F	Seeded From UniProt	complete
involved_in	GO:0061002	negative regulation of dendritic spine morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	P	Seeded From UniProt	complete
involved_in	GO:0060999	positive regulation of dendritic spine development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	P	Seeded From UniProt	complete
involved_in	GO:0051965	positive regulation of synapse assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	P	Seeded From UniProt	complete
involved_in	GO:0031175	neuron projection development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	P	Seeded From UniProt	complete
enables	GO:0030165	PDZ domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8N2Q7 ensembl:ENSP00000392500	F	Seeded From UniProt	complete
involved_in	GO:2000809	positive regulation of synaptic vesicle clustering	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:2000310	regulation of NMDA receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:2000302	positive regulation of synaptic vesicle exocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:1904861	excitatory synapse assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:1900244	positive regulation of synaptic vesicle endocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0099560	synaptic membrane adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	C	Seeded From UniProt	complete
involved_in	GO:0098698	postsynaptic specialization assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097120	receptor localization to synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097119	postsynaptic density protein 95 clustering	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097115	neurexin clustering involved in presynaptic membrane assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097113	AMPA glutamate receptor clustering	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097105	presynaptic membrane assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097104	postsynaptic membrane assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0097091	synaptic vesicle clustering	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0072553	terminal button organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0061002	negative regulation of dendritic spine morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0060999	positive regulation of dendritic spine development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0051965	positive regulation of synapse assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0050808	synapse organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0050804	modulation of chemical synaptic transmission	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0048789	cytoskeletal matrix organization at active zone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0045664	regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	C	Seeded From UniProt	complete
involved_in	GO:0045184	establishment of protein localization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
enables	GO:0042043	neurexin family protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	F	Seeded From UniProt	complete
involved_in	GO:0035418	protein localization to synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0016080	synaptic vesicle targeting	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0010841	positive regulation of circadian sleep/wake cycle, wakefulness	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	C	Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	C	Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0007158	neuron cell-cell adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
involved_in	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	C	Seeded From UniProt	complete
involved_in	GO:0002087	regulation of respiratory gaseous exchange by neurological system process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99K10 ensembl:ENSMUSP00000142200	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030022	C	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030022	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000460	C	Seeded From UniProt	complete
enables	GO:0042043	neurexin family protein binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000460 InterPro:IPR030022	F	Seeded From UniProt	complete
involved_in	GO:0050804	modulation of chemical synaptic transmission	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030022	P	Seeded From UniProt	complete
involved_in	GO:0050808	synapse organization	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030022	P	Seeded From UniProt	complete
part_of	GO:0060076	excitatory synapse	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR030022	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 ^1.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

CHICK:D2X2H3

Contents

Annotations

Notes

References

a

c

d

e

g

h

i

m

n

p

r

s

t

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools