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CHICK:CP2H1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CYP2H1
Protein Name(s) Cytochrome P450 2H1

CYPIIH1 Cytochrome P450 PB15 Cytochrome P450 PCHP3

External Links
UniProt P05180
EMBL M13454
PIR A24814
RefSeq NP_001001616.1
UniGene Gga.858
ProteinModelPortal P05180
SMR P05180
PaxDb P05180
GeneID 414746
KEGG gga:414746
CTD 414746
eggNOG COG2124
HOGENOM HOG000036992
HOVERGEN HBG015789
InParanoid P05180
KO K17853
PhylomeDB P05180
NextBio 20818715
PRO PR:P05180
Proteomes UP000000539
GO GO:0005789
GO:0070330
GO:0020037
GO:0005506
Gene3D 1.10.630.10
InterPro IPR001128
IPR017972
IPR002401
Pfam PF00067
PRINTS PR00463
PR00385
SUPFAM SSF48264
PROSITE PS00086

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0042493

response to drug

PMID:11518807[1]

ECO:0000314

direct assay evidence used in manual assertion

P

  • has_participant:(CHEBI:8069)
  • occurs_in:(UBERON:0002107)
  • occurs_in:(CL:0000182)|has_participant(CHEBI:5439)
  • occurs_in:(UBERON:0002107)
  • occurs_in:(CL:0000182)|has_participant(CHEBI:44241)
  • occurs_in:(UBERON:0002107)
  • occurs_in:(CL:0000182)

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:25229839[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002107)

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919332
MGI:MGI:2147497
MGI:MGI:3642960
PANTHER:PTN000670347
RGD:2475
UniProtKB:P05181
UniProtKB:P10632
UniProtKB:P10635
UniProtKB:P11712
UniProtKB:P20813
UniProtKB:P33261

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000670347
RGD:1306078
RGD:1311866
RGD:2463
RGD:2466
RGD:2467
RGD:2471
RGD:2475
RGD:620007
RGD:620370
RGD:620379
RGD:620640
RGD:628627
UniProtKB:P11712
UniProtKB:P24903
WB:WBGene00018334

C

Seeded From UniProt

complete

involved_in

GO:0042738

exogenous drug catabolic process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000670347
UniProtKB:A0A087X1C5
UniProtKB:P10632
UniProtKB:P11509
UniProtKB:P11712
UniProtKB:P20813
UniProtKB:P33261

P

Seeded From UniProt

complete

enables

GO:0020037

heme binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000670347
UniProtKB:P05181
UniProtKB:P10635
UniProtKB:P11509
UniProtKB:P20813
UniProtKB:P33261
UniProtKB:Q16696

F

Seeded From UniProt

complete

involved_in

GO:0019373

epoxygenase P450 pathway

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002387263
RGD:620088

P

Seeded From UniProt

complete

enables

GO:0016712

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000670347
RGD:2475
UniProtKB:P24903

F

Seeded From UniProt

complete

enables

GO:0008395

steroid hydroxylase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010383
PANTHER:PTN001210788
RGD:2463
RGD:2464
RGD:2466
RGD:2467
UniProtKB:P11712
UniProtKB:P33261

F

Seeded From UniProt

complete

enables

GO:0008392

arachidonic acid epoxygenase activity

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1919332
MGI:MGI:2147497
MGI:MGI:3642960
PANTHER:PTN002387263
RGD:620370

F

Seeded From UniProt

complete

involved_in

GO:0006805

xenobiotic metabolic process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000670347
RGD:2475
UniProtKB:A0A087X1C5
UniProtKB:P20813
UniProtKB:Q8TAV3

P

Seeded From UniProt

complete

involved_in

GO:0006082

organic acid metabolic process

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000670347
UniProtKB:P10632

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1929474
PANTHER:PTN000670347
RGD:708427
UniProtKB:A0A087X1C5
WB:WBGene00000905

C

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0016705

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR036396

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001128
InterPro:IPR002401
InterPro:IPR017972
InterPro:IPR036396

P

Seeded From UniProt

complete

enables

GO:0070330

aromatase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.14.1

F

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256

C

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0492

C

Seeded From UniProt

complete

part_of

GO:0031090

organelle membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0165

C

Seeded From UniProt

complete

part_of

GO:0005789

endoplasmic reticulum membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0097

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Handschin, C et al. (2001) Conservation of signaling pathways of xenobiotic-sensing orphan nuclear receptors, chicken xenobiotic receptor, constitutive androstane receptor, and pregnane X receptor, from birds to humans. Mol. Endocrinol. 15 1571-85 PubMed GONUTS page
  2. Watanabe, KP et al. (2015) Partial cloning of CYP2C23a genes and hepatic protein expression in eight representative avian species. J. Vet. Pharmacol. Ther. 38 190-5 PubMed GONUTS page
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page