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CHICK:CP1A5
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | CYP1A5 | |
| Protein Name(s) | Cytochrome P450 1A5
CYPIA5 Cytochrome P450 TCDDAA | |
| External Links | ||
| UniProt | P79761 | |
| EMBL | X99454 | |
| RefSeq | NP_990477.1 | |
| UniGene | Gga.48615 | |
| ProteinModelPortal | P79761 | |
| SMR | P79761 | |
| STRING | 9031.ENSGALP00000002010 | |
| PaxDb | P79761 | |
| GeneID | 396051 | |
| KEGG | gga:396051 | |
| CTD | 1543 | |
| eggNOG | COG2124 | |
| HOVERGEN | HBG106944 | |
| InParanoid | P79761 | |
| KO | K07408 | |
| PhylomeDB | P79761 | |
| NextBio | 20816111 | |
| PRO | PR:P79761 | |
| Proteomes | UP000000539 | |
| GO | GO:0005789 GO:0070330 GO:0020037 GO:0005506 | |
| Gene3D | 1.10.630.10 | |
| InterPro | IPR001128 IPR017972 IPR002401 IPR008066 | |
| Pfam | PF00067 | |
| PRINTS | PR00463 PR01683 PR00385 | |
| SUPFAM | SSF48264 | |
| PROSITE | PS00086 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0043385 |
mycotoxin metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
has_direct_input:(CHEBI:9381) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071615 |
oxidative deethylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019825 |
oxygen binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071615 |
oxidative deethylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070989 |
oxidative demethylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005623 |
cell |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0002107) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0017144 |
drug metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046677 |
response to antibiotic |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019825 |
oxygen binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001210461 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004497 |
monooxygenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:88588 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005506 |
iron ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0020037 |
heme binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR001128 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070330 |
aromatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004497 |
monooxygenase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031090 |
organelle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Shang, S et al. (2013) Chicken cytochrome P450 1A5 is the key enzyme for metabolizing T-2 toxin to 3'OH-T-2. Int J Mol Sci 14 10809-18 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Yang, J et al. (2013) Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 157 337-43 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Zhang, LL et al. (2011) Effects of fluoroquinolones on CYP4501A and 3A in male broilers. Res. Vet. Sci. 90 99-105 PubMed GONUTS page
- ↑ Sinclair, PR et al. (1997) Identification of CYP1A5 as the CYP1A enzyme mainly responsible for uroporphyrinogen oxidation induced by AH receptor ligands in chicken liver and kidney. Drug Metab. Dispos. 25 779-83 PubMed GONUTS page
- ↑ 5.0 5.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
e
m
o
- GO:0005623 ! obsolete cell
- GO:0055114 ! obsolete oxidation-reduction process
- GO:0071615 ! obsolete oxidative deethylation
- GO:0031090 ! organelle membrane
- GO:0070989 ! oxidative demethylation
- GO:0016491 ! oxidoreductase activity
- GO:0016712 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
- GO:0016705 ! oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
- GO:0019825 ! oxygen binding
