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CHICK:CDC42

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CDC42
Protein Name(s) Cell division control protein 42 homolog

G25K GTP-binding protein

External Links
UniProt Q90694
EMBL U40848
RefSeq NP_990379.1
UniGene Gga.4438
ProteinModelPortal Q90694
SMR Q90694
MINT MINT-126406
STRING 9031.ENSGALP00000007641
BindingDB Q90694
PaxDb Q90694
PRIDE Q90694
Ensembl ENSGALT00000034897
GeneID 395917
KEGG gga:395917
CTD 998
eggNOG COG1100
GeneTree ENSGT00760000118978
HOGENOM HOG000233974
HOVERGEN HBG009351
InParanoid Q90694
KO K04393
OMA VITIDQG
OrthoDB EOG764747
PhylomeDB Q90694
Reactome REACT_277148
REACT_285183
REACT_286472
REACT_286768
REACT_299011
REACT_329539
REACT_332376
REACT_334706
REACT_345024
REACT_357253
REACT_359218
REACT_359333
REACT_359432
REACT_360300
NextBio 20815982
PRO PR:Q90694
Proteomes UP000000539
GO GO:0005912
GO:0045177
GO:0042995
GO:0005911
GO:0005737
GO:0036464
GO:0070062
GO:0030175
GO:0005925
GO:0031256
GO:0030496
GO:0072686
GO:0043209
GO:0043005
GO:0043025
GO:0005886
GO:0051233
GO:0005525
GO:0003924
GO:0030036
GO:0051017
GO:0034332
GO:0060070
GO:0003161
GO:0034613
GO:0036336
GO:0006897
GO:0048730
GO:0090136
GO:0060684
GO:0035088
GO:0046847
GO:0060047
GO:0031424
GO:0003334
GO:0045185
GO:0008152
GO:0035264
GO:0010629
GO:0031333
GO:0048664
GO:0007097
GO:0032467
GO:0060501
GO:0010628
GO:0071338
GO:0043410
GO:0033138
GO:0043552
GO:0045860
GO:0031274
GO:1900026
GO:0051988
GO:0051489
GO:0007088
GO:0042176
GO:0043497
GO:0031647
GO:0007264
GO:0021762
Gene3D 3.40.50.300
InterPro IPR027417
IPR005225
IPR001806
IPR003578
Pfam PF00071
PRINTS PR00449
SMART SM00174
SUPFAM SSF52540
TIGRFAMs TIGR00231
PROSITE PS51420

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007015

actin filament organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0006911

phagocytosis, engulfment

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0045198

establishment of epithelial cell apical/basal polarity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0034329

cell junction assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0060997

dendritic spine morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60766

P

Seeded From UniProt

complete

involved_in

GO:0046847

filopodium assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60766

P

Seeded From UniProt

complete

involved_in

GO:0045860

positive regulation of protein kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P40793

P

Seeded From UniProt

complete

involved_in

GO:0045185

maintenance of protein location

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P40793

P

Seeded From UniProt

complete

involved_in

GO:0043552

positive regulation of phosphatidylinositol 3-kinase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60766

P

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60766

C

Seeded From UniProt

complete

involved_in

GO:0031333

negative regulation of protein complex assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0031274

positive regulation of pseudopodium assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

C

Seeded From UniProt

complete

involved_in

GO:0030036

actin cytoskeleton organization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

part_of

GO:0005912

adherens junction

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P40793

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

C

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60766

F

Seeded From UniProt

complete

part_of

GO:0072686

mitotic spindle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

C

Seeded From UniProt

complete

involved_in

GO:0051988

regulation of attachment of spindle microtubules to kinetochore

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0051489

regulation of filopodium assembly

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

part_of

GO:0051233

spindle midzone

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

C

Seeded From UniProt

complete

involved_in

GO:0032467

positive regulation of cytokinesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

P

Seeded From UniProt

complete

part_of

GO:0030496

midbody

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60953

C

Seeded From UniProt

complete

involved_in

GO:0099563

modification of synaptic structure

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000633069
RGD:71043

P

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000633069
UniProtKB:P60953

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000633069
UniProtKB:P60953

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106211
PANTHER:PTN001530052

C

Seeded From UniProt

complete

involved_in

GO:0032956

regulation of actin cytoskeleton organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001530052
dictyBase:DDB_G0268622
dictyBase:DDB_G0279605

P

Seeded From UniProt

complete

involved_in

GO:0032488

Cdc42 protein signal transduction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000632904
RGD:71043

P

Seeded From UniProt

complete

involved_in

GO:0030036

actin cytoskeleton organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1916831
MGI:MGI:1931551
PANTHER:PTN001530052
UniProtKB:P60953
UniProtKB:P84095
UniProtKB:Q9H4E5

P

Seeded From UniProt

complete

involved_in

GO:0030031

cell projection assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
PANTHER:PTN000632904

P

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
MGI:MGI:106211
PANTHER:PTN001530052
UniProtKB:P60953
dictyBase:DDB_G0268622
dictyBase:DDB_G0269176
dictyBase:DDB_G0277869
dictyBase:DDB_G0282365

F

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
MGI:MGI:1916831
MGI:MGI:1931551
MGI:MGI:1931553
PANTHER:PTN001530052
UniProtKB:Q7L0Q8
dictyBase:DDB_G0268622

P

Seeded From UniProt

complete

involved_in

GO:0007266

Rho protein signal transduction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
FB:FBgn0014011
MGI:MGI:1931551
PANTHER:PTN000632671
RGD:619921
UniProtKB:I3LVS7
UniProtKB:P61586
UniProtKB:P84095

P

Seeded From UniProt

complete

involved_in

GO:0007163

establishment or maintenance of cell polarity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001530052
UniProtKB:G5EAY4
UniProtKB:Q4WWL5
WB:WBGene00000390
WB:WBGene00009059

P

Seeded From UniProt

complete

involved_in

GO:0007015

actin filament organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001530052
RGD:71043
UniProtKB:P60953

P

Seeded From UniProt

complete

involved_in

GO:0006897

endocytosis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106211
PANTHER:PTN000632904

P

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
PANTHER:PTN001530052
WB:WBGene00000390
dictyBase:DDB_G0277869

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106211
MGI:MGI:1921984
PANTHER:PTN001530052
PomBase:SPAC110.03
RGD:621626
RGD:71043
SGD:S000004219
UniProtKB:P17081
UniProtKB:P60953
WB:WBGene00000390

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
MGI:MGI:106211
MGI:MGI:1920546
MGI:MGI:1921984
PANTHER:PTN001530052
UniProtKB:P60953
UniProtKB:Q15669
WB:WBGene00000390
dictyBase:DDB_G0279605

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0039140
MGI:MGI:108446
MGI:MGI:97845
PANTHER:PTN000632671
RGD:619755
RGD:619921
RGD:71043
SGD:S000001380
TAIR:locus:2131606
TAIR:locus:2204380
UniProtKB:A0A1D8PDV5
UniProtKB:P15153
UniProtKB:P60953
UniProtKB:P61586
UniProtKB:P63000
UniProtKB:Q15669
UniProtKB:Q9SSX0
WB:WBGene00000390
WB:WBGene00000424
WB:WBGene00004287
WB:WBGene00004357

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
FB:FBgn0010341
FB:FBgn0014011
FB:FBgn0014020
MGI:MGI:106211
MGI:MGI:1096342
MGI:MGI:1916831
MGI:MGI:97845
MGI:MGI:97846
PANTHER:PTN000632671
PomBase:SPAC110.03
PomBase:SPAC16.01
PomBase:SPAC16A10.04
PomBase:SPAC1F7.04
PomBase:SPAC23C4.08
RGD:619755
RGD:619921
SGD:S000000046
SGD:S000001380
SGD:S000001763
SGD:S000004219
SGD:S000005034
SGD:S000005124
SGD:S000006369
TAIR:locus:2099232
TAIR:locus:2131606
UniProtKB:A0A1D8PCX9
UniProtKB:A0A1D8PH96
UniProtKB:P17081
UniProtKB:P60763
UniProtKB:P60953
UniProtKB:P61586
UniProtKB:P63000
UniProtKB:P84095
UniProtKB:Q5A904
WB:WBGene00000390
WB:WBGene00000424
WB:WBGene00003239
WB:WBGene00004287
WB:WBGene00004357

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806
InterPro:IPR037874

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806
InterPro:IPR003578
InterPro:IPR005225

F

Seeded From UniProt

complete

involved_in

GO:0007264

small GTPase mediated signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003578

P

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0030496

midbody

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0469

C

Seeded From UniProt

complete

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Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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