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CHICK:CAD13

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CDH13
Protein Name(s) Cadherin-13

Truncated cadherin T-cad T-cadherin

External Links
UniProt P33150
EMBL M81779
S62757
PIR I51206
JU0279
RefSeq NP_001001760.1
UniGene Gga.24273
PDB 3K5S
3K6I
PDBsum 3K5S
3K6I
ProteinModelPortal P33150
SMR P33150
DIP DIP-58996N
STRING 9031.ENSGALP00000038306
PaxDb P33150
GeneID 414849
KEGG gga:414849
CTD 1012
eggNOG NOG304703
HOGENOM HOG000231254
HOVERGEN HBG106438
InParanoid P33150
KO K06808
PhylomeDB P33150
EvolutionaryTrace P33150
NextBio 20818745
PRO PR:P33150
Proteomes UP000000539
GO GO:0031225
GO:0005886
GO:0005509
GO:0007156
Gene3D 2.60.40.60
InterPro IPR002126
IPR015919
IPR020894
IPR014868
Pfam PF00028
PF08758
PRINTS PR00205
SMART SM00112
SM01055
SUPFAM SSF49313
PROSITE PS00232
PS50268

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0099512

supramolecular fiber

PMID:1707785[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002329)|part_of:(UBERON:0003089)|part_of:(UBERON:0003082)

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:1707785[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002329)|part_of:(UBERON:0003089)|part_of:(UBERON:0003082)

Seeded From UniProt

complete

involved_in

GO:0098609

cell-cell adhesion

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105057
MGI:MGI:88354
MGI:MGI:88356
PANTHER:PTN000616280
RGD:69280
UniProtKB:O93319
UniProtKB:P12830
UniProtKB:Q86UP0

P

Seeded From UniProt

complete

enables

GO:0045296

cadherin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000616280
UniProtKB:P10288
UniProtKB:P55290

F

Seeded From UniProt

complete

involved_in

GO:0044331

cell-cell adhesion mediated by cadherin

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88355
PANTHER:PTN000616280
UniProtKB:P10288

P

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:99551
PANTHER:PTN000616280

F

Seeded From UniProt

complete

involved_in

GO:0034332

adherens junction organization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000616280
UniProtKB:P12830
ZFIN:ZDB-GENE-990415-171

P

Seeded From UniProt

complete

part_of

GO:0016342

catenin complex

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88354
PANTHER:PTN000616280
UniProtKB:P12830
UniProtKB:P19022
ZFIN:ZDB-GENE-990415-171

C

Seeded From UniProt

complete

involved_in

GO:0016339

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1095414
MGI:MGI:88354
MGI:MGI:88355
PANTHER:PTN000616280
RGD:2321
RGD:69280
UniProtKB:P55290

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1095414
MGI:MGI:88354
MGI:MGI:88355
PANTHER:PTN000616280
UniProtKB:P10288
UniProtKB:P33150
UniProtKB:P33151

C

Seeded From UniProt

complete

enables

GO:0008092

cytoskeletal protein binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88354
PANTHER:PTN000616280

F

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1095414
MGI:MGI:88355
MGI:MGI:99218
PANTHER:PTN000616280
UniProtKB:P55290

P

Seeded From UniProt

complete

involved_in

GO:0007043

cell-cell junction assembly

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000616280
UniProtKB:P33151

P

Seeded From UniProt

complete

part_of

GO:0005913

cell-cell adherens junction

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105057
MGI:MGI:88354
MGI:MGI:88356
PANTHER:PTN000616280
RGD:69280
UniProtKB:P10288
UniProtKB:P12830
UniProtKB:P19022
UniProtKB:P33151

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:105057
MGI:MGI:107435
MGI:MGI:1095414
MGI:MGI:88354
MGI:MGI:88355
MGI:MGI:88356
MGI:MGI:99217
MGI:MGI:99551
PANTHER:PTN000616280
RGD:619745
RGD:621089
RGD:69279
RGD:69280
UniProtKB:O93319
UniProtKB:P10288
UniProtKB:P12830
UniProtKB:P19022
UniProtKB:P22223
UniProtKB:P33151
UniProtKB:P55283
UniProtKB:P55290
UniProtKB:Q6ZTQ4
UniProtKB:Q90763
ZFIN:ZDB-GENE-010606-1

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88354
PANTHER:PTN000616280
UniProtKB:Q86UP0

F

Seeded From UniProt

complete

involved_in

GO:0002040

sprouting angiogenesis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000616660
UniProtKB:P55290

P

Seeded From UniProt

complete

involved_in

GO:0000902

cell morphogenesis

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000616280
ZFIN:ZDB-GENE-990415-171

P

Seeded From UniProt

complete

enables

GO:0071813

lipoprotein particle binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

F

Seeded From UniProt

complete

involved_in

GO:0055096

low-density lipoprotein particle mediated signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0051668

localization within membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0050927

positive regulation of positive chemotaxis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0050850

positive regulation of calcium-mediated signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0048661

positive regulation of smooth muscle cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0045944

positive regulation of transcription by RNA polymerase II

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

enables

GO:0045296

cadherin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

F

Seeded From UniProt

complete

involved_in

GO:0043616

keratinocyte proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0043542

endothelial cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

C

Seeded From UniProt

complete

involved_in

GO:0042058

regulation of epidermal growth factor receptor signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

enables

GO:0030169

low-density lipoprotein particle binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

F

Seeded From UniProt

complete

involved_in

GO:0030100

regulation of endocytosis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0030032

lamellipodium assembly

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0016601

Rac protein signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0016339

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0008285

negative regulation of cell population proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0007266

Rho protein signal transduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0007162

negative regulation of cell adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

part_of

GO:0005901

caveola

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

C

Seeded From UniProt

complete

involved_in

GO:0002040

sprouting angiogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0001954

positive regulation of cell-matrix adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

involved_in

GO:0001938

positive regulation of endothelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P55290
ensembl:ENSP00000268613

P

Seeded From UniProt

complete

enables

GO:0055100

adiponectin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WTR5
ensembl:ENSMUSP00000113527

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WTR5
ensembl:ENSMUSP00000113527

F

Seeded From UniProt

complete

part_of

GO:0009897

external side of plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WTR5
ensembl:ENSMUSP00000113527

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9WTR5
ensembl:ENSMUSP00000113527

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126
InterPro:IPR015919

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020894

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR020894
InterPro:IPR033216

P

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002126
InterPro:IPR015919

C

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033216

F

Seeded From UniProt

complete

involved_in

GO:0098609

cell-cell adhesion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039808

P

Seeded From UniProt

complete

part_of

GO:0099512

supramolecular fiber

PMID:1707785[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002329)|part_of:(UBERON:0003089)|part_of:(UBERON:0003082)

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:1707785[1]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0002329)|part_of:(UBERON:0003089)|part_of:(UBERON:0003082)

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0031225

anchored component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0336

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Ranscht, B & Bronner-Fraser, M (1991) T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo. Development 111 15-22 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page