CHICK:CAC1D

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	CACNA1D
Protein Name(s)	Voltage-dependent L-type calcium channel subunit alpha-1D CHCACHA1D Voltage-gated calcium channel subunit alpha Cav1.3
External Links
UniProt	O73700
EMBL	AF027602 AF027603 AF027604 AF027605 AF027606
RefSeq	NP_990365.1
UniGene	Gga.51515 Gga.51516 Gga.52031 Gga.528
ProteinModelPortal	O73700
SMR	O73700
STRING	9031.ENSGALP00000008540
PaxDb	O73700
PRIDE	O73700
GeneID	395895
KEGG	gga:395895
CTD	776
eggNOG	COG1226
HOGENOM	HOG000231529
HOVERGEN	HBG050763
InParanoid	O73700
KO	K04851
PhylomeDB	O73700
NextBio	20815960
PRO	PR:O73700
Proteomes	UP000000539
GO	GO:0005891 GO:0046872 GO:0005245
Gene3D	1.20.120.350
InterPro	IPR027359 IPR005821 IPR005452 IPR014873 IPR005446 IPR002077
PANTHER	PTHR10037:SF139
Pfam	PF08763 PF00520
PRINTS	PR00167 PR01630 PR01636
SMART	SM01062

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0070509	calcium ion import	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001295314 RGD:2244 RGD:2245 RGD:2246 RGD:628852 RGD:70973 UniProtKB:Q01668	P	Seeded From UniProt	complete
enables	GO:0008331	high voltage-gated calcium channel activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:88293 PANTHER:PTN000004694 RGD:2245 RGD:70973 RGD:70983 UniProtKB:O60840 UniProtKB:Q01668 UniProtKB:Q13698 UniProtKB:Q13936	F	Seeded From UniProt	complete
involved_in	GO:0006816	calcium ion transport	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0263111 MGI:MGI:103013 MGI:MGI:106217 MGI:MGI:109482 MGI:MGI:88294 MGI:MGI:88296 PANTHER:PTN001295293 RGD:2244 RGD:2245 RGD:628852 RGD:70973 RGD:70983 SGD:S000003449 UniProtKB:Q01668 UniProtKB:Q13698 ZFIN:ZDB-GENE-020129-1	P	Seeded From UniProt	complete
enables	GO:0005245	voltage-gated calcium channel activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0001991 FB:FBgn0263111 MGI:MGI:103013 MGI:MGI:106217 MGI:MGI:109482 MGI:MGI:1859639 MGI:MGI:88294 MGI:MGI:88296 PANTHER:PTN001295314 RGD:2244 RGD:2245 RGD:2246 RGD:628852 RGD:70973 UniProtKB:O00555 UniProtKB:O60840 UniProtKB:Q01668 UniProtKB:Q13698 UniProtKB:Q13936 UniProtKB:Q15878 WB:WBGene00001187	F	Seeded From UniProt	complete
involved_in	GO:0099533	positive regulation of presynaptic cytosolic calcium concentration	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0099635	P	Seeded From UniProt	complete
involved_in	GO:0099703	induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0099635	P	Seeded From UniProt	complete
part_of	GO:1990454	L-type voltage-gated calcium channel complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	C	Seeded From UniProt	complete
involved_in	GO:0086091	regulation of heart rate by cardiac conduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
enables	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	F	Seeded From UniProt	complete
involved_in	GO:0086046	membrane depolarization during SA node cell action potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
involved_in	GO:0086002	cardiac muscle cell action potential involved in contraction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
involved_in	GO:0070509	calcium ion import	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
involved_in	GO:0051928	positive regulation of calcium ion transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
enables	GO:0051393	alpha-actinin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	F	Seeded From UniProt	complete
enables	GO:0008331	high voltage-gated calcium channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	F	Seeded From UniProt	complete
involved_in	GO:0007605	sensory perception of sound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
involved_in	GO:0006816	calcium ion transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	P	Seeded From UniProt	complete
part_of	GO:0005891	voltage-gated calcium channel complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	C	Seeded From UniProt	complete
enables	GO:0005262	calcium channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	F	Seeded From UniProt	complete
enables	GO:0005245	voltage-gated calcium channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q01668 ensembl:ENSP00000288139	F	Seeded From UniProt	complete
involved_in	GO:1901379	regulation of potassium ion transmembrane transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
involved_in	GO:1901016	regulation of potassium ion transmembrane transporter activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
enables	GO:0099635	voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	F	Seeded From UniProt	complete
part_of	GO:0099059	integral component of presynaptic active zone membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	C	Seeded From UniProt	complete
part_of	GO:0098683	cochlear hair cell ribbon synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	C	Seeded From UniProt	complete
involved_in	GO:0086091	regulation of heart rate by cardiac conduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
enables	GO:0086059	voltage-gated calcium channel activity involved SA node cell action potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	F	Seeded From UniProt	complete
involved_in	GO:0086046	membrane depolarization during SA node cell action potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
involved_in	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
involved_in	GO:0045762	positive regulation of adenylate cyclase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
enables	GO:0030506	ankyrin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	F	Seeded From UniProt	complete
part_of	GO:0030018	Z disc	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	C	Seeded From UniProt	complete
enables	GO:0008331	high voltage-gated calcium channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	F	Seeded From UniProt	complete
involved_in	GO:0007605	sensory perception of sound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
involved_in	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q99246 ensembl:ENSMUSP00000107869	C	Seeded From UniProt	complete
enables	GO:0005216	ion channel activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	F	Seeded From UniProt	complete
enables	GO:0005245	voltage-gated calcium channel activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002077 InterPro:IPR005446 InterPro:IPR005452	F	Seeded From UniProt	complete
part_of	GO:0005891	voltage-gated calcium channel complex	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002077 InterPro:IPR005446 InterPro:IPR005452	C	Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	C	Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005821	P	Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002077 InterPro:IPR005446 InterPro:IPR005452	P	Seeded From UniProt	complete
involved_in	GO:0006816	calcium ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0109	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
enables	GO:0005262	calcium channel activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0107	F	Seeded From UniProt	complete
involved_in	GO:0070588	calcium ion transmembrane transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0107	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0406	P	Seeded From UniProt	complete
involved_in	GO:0034765	regulation of ion transmembrane transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0851	P	Seeded From UniProt	complete
enables	GO:0005244	voltage-gated ion channel activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0851	F	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:CAC1D

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