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CHICK:BLNK
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | BLNK (synonyms: BASH) | |
| Protein Name(s) | B-cell linker protein
B-cell adapter SH2 domain-containing protein Cytoplasmic adapter protein Src homology 2 domain-containing leukocyte protein of 65 kDa SLP-65 | |
| External Links | ||
| UniProt | Q9YGC1 | |
| EMBL | AB015289 AF089727 | |
| RefSeq | NP_990239.1 | |
| UniGene | Gga.3738 | |
| ProteinModelPortal | Q9YGC1 | |
| SMR | Q9YGC1 | |
| BioGrid | 676007 | |
| IntAct | Q9YGC1 | |
| STRING | 9031.ENSGALP00000011282 | |
| PaxDb | Q9YGC1 | |
| Ensembl | ENSGALT00000011296 | |
| GeneID | 395733 | |
| KEGG | gga:395733 | |
| CTD | 29760 | |
| eggNOG | NOG44661 | |
| GeneTree | ENSGT00530000063094 | |
| HOGENOM | HOG000088646 | |
| HOVERGEN | HBG053147 | |
| InParanoid | Q9YGC1 | |
| KO | K07371 | |
| OrthoDB | EOG7WMCKM | |
| PhylomeDB | Q9YGC1 | |
| TreeFam | TF326567 | |
| Reactome | REACT_351340 | |
| NextBio | 20815801 | |
| PRO | PR:Q9YGC1 | |
| Proteomes | UP000000539 | |
| ExpressionAtlas | Q9YGC1 | |
| GO | GO:0005737 GO:0005829 GO:0005886 GO:0005070 GO:0005068 GO:0042113 GO:0006955 GO:0035556 GO:0009967 GO:0007169 | |
| Gene3D | 3.30.505.10 | |
| InterPro | IPR000980 | |
| Pfam | PF00017 | |
| SMART | SM00252 | |
| SUPFAM | SSF55550 | |
| PROSITE | PS50001 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0007202 |
activation of phospholipase C activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001019935 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1351468 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96878 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005070 |
SH3/SH2 adaptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000363867 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009967 |
positive regulation of signal transduction |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005070 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051726 |
regulation of cell cycle |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030183 |
B cell differentiation |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-GGA-912730 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042113 |
B cell activation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ishiai, M et al. (1999) BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells. Immunity 10 117-25 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 Gupta, N et al. (2008) Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins. Cancer Res. 68 808-14 PubMed GONUTS page
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