CHICK:ATG7

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ATG7 (synonyms: APG7L)
Protein Name(s)	Ubiquitin-like modifier-activating enzyme ATG7 ATG12-activating enzyme E1 ATG7 Autophagy-related protein 7 APG7-like
External Links
UniProt	Q5ZKY2
EMBL	AJ719952
RefSeq	NP_001025763.1
UniGene	Gga.22358
ProteinModelPortal	Q5ZKY2
STRING	9031.ENSGALP00000007877
PaxDb	Q5ZKY2
Ensembl	ENSGALT00000036275
GeneID	415961
KEGG	gga:415961
CTD	10533
eggNOG	COG0476
GeneTree	ENSGT00390000017509
HOGENOM	HOG000162379
HOVERGEN	HBG080877
InParanoid	Q5ZKY2
KO	K08337
OMA	YDPCHLP
PhylomeDB	Q5ZKY2
NextBio	20819485
PRO	PR:Q5ZKY2
Proteomes	UP000000539
GO	GO:0005829 GO:0000407 GO:0019778 GO:0019779 GO:0007628 GO:0006501 GO:0055013 GO:0006520 GO:0071455 GO:0006995 GO:0021955 GO:0021680 GO:0021987 GO:0051607 GO:0044805 GO:0001889 GO:0016236 GO:0000422 GO:0043066 GO:2000619 GO:0039689 GO:0050877 GO:0034727 GO:0043065 GO:0016239 GO:0070257 GO:0045732 GO:0031401 GO:0009791 GO:0030163 GO:0032446 GO:0015031 GO:0021860 GO:1903146 GO:0031396 GO:0039521
Gene3D	3.40.50.720
InterPro	IPR006285 IPR009036 IPR016040 IPR000594
PANTHER	PTHR10953:SF3
Pfam	PF00899
SUPFAM	SSF69572
TIGRFAMs	TIGR01381

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0042752	regulation of circadian rhythm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9D906	P	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9D906	P	Seeded From UniProt	complete
enables	GO:0019778	Atg12 activating enzyme activity	PMID:20723759^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9D906	F	Seeded From UniProt	complete
involved_in	GO:0044805	late nucleophagy	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000102341 SGD:S000001214	P	Seeded From UniProt	complete
involved_in	GO:0034727	piecemeal microautophagy of the nucleus	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000102341 SGD:S000001214	P	Seeded From UniProt	complete
involved_in	GO:0032446	protein modification by small protein conjugation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0023143 FB:FBgn0029113 FB:FBgn0029512 FB:FBgn0032054 FB:FBgn0034366 FB:FBgn0261112 FB:FBgn0263697 MGI:MGI:1913894 MGI:MGI:1913913 MGI:MGI:1921494 MGI:MGI:98890 MGI:MGI:98891 PANTHER:PTN000102039 PomBase:SPAC4C5.04 PomBase:SPBC1604.21c PomBase:SPBC16H5.03c SGD:S000001153 SGD:S000001214 SGD:S000001693 SGD:S000002798 SGD:S000005924 SGD:S000006270 SGD:S000006384 TAIR:locus:2060854 TAIR:locus:2159727 TAIR:locus:2164270 TAIR:locus:2832477 UniProtKB:A0AVT1 UniProtKB:P22314 UniProtKB:P41226 UniProtKB:P42744 UniProtKB:Q13564 UniProtKB:Q5BAI0 UniProtKB:Q8I553 UniProtKB:Q8I5F9 UniProtKB:Q8IDZ6 UniProtKB:Q9GZZ9 UniProtKB:Q9SJT1 UniProtKB:Q9UBE0 UniProtKB:Q9UBT2 UniProtKB:Q9ZV69 WB:WBGene00000142 WB:WBGene00004341 WB:WBGene00006699 WB:WBGene00006700 ZFIN:ZDB-GENE-040625-21	P	Seeded From UniProt	complete
enables	GO:0019779	Atg8 activating enzyme activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0034366 MGI:MGI:1921494 PANTHER:PTN000102341 SGD:S000001214	F	Seeded From UniProt	complete
enables	GO:0019778	Atg12 activating enzyme activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1921494 PANTHER:PTN000102341 SGD:S000001214	F	Seeded From UniProt	complete
involved_in	GO:0006995	cellular response to nitrogen starvation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000102341 dictyBase:DDB_G0271096	P	Seeded From UniProt	complete
involved_in	GO:0006501	C-terminal protein lipidation	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000102341 SGD:S000001214	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10154 EcoGene:EG11587 FB:FBgn0029113 FB:FBgn0032054 MGI:MGI:1921494 PANTHER:PTN000102040 PomBase:SPBC1604.21c SGD:S000001214 SGD:S000001693 SGD:S000006384 TAIR:locus:2060854 TAIR:locus:2152375 TAIR:locus:2164270 TAIR:locus:2207185 UniProtKB:A0AVT1 UniProtKB:O95352 UniProtKB:O95396 UniProtKB:P42744 UniProtKB:Q8I5F9 UniProtKB:Q8ID54 UniProtKB:Q8IDZ6 UniProtKB:Q9GZZ9 UniProtKB:Q9SJT1 UniProtKB:Q9ZV69 WB:WBGene00004341 dictyBase:DDB_G0271096	C	Seeded From UniProt	complete
involved_in	GO:0000422	autophagy of mitochondrion	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1921494 PANTHER:PTN000102341 SGD:S000001214 UniProtKB:O95352	P	Seeded From UniProt	complete
part_of	GO:0000407	phagophore assembly site	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000102341 SGD:S000001214	C	Seeded From UniProt	complete
involved_in	GO:0000045	autophagosome assembly	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1921494 PANTHER:PTN000102341 UniProtKB:A0A0G2KPR3	P	Seeded From UniProt	complete
involved_in	GO:0075044	autophagy of host cells involved in interaction with symbiont	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0071455	cellular response to hyperoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0045732	positive regulation of protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0043065	positive regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	F	Seeded From UniProt	complete
involved_in	GO:0039521	suppression by virus of host autophagy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0031401	positive regulation of protein modification process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0016236	macroautophagy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0009267	cellular response to starvation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	F	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
involved_in	GO:0006497	protein lipidation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	C	Seeded From UniProt	complete
involved_in	GO:0000422	autophagy of mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O95352 ensembl:ENSP00000346437	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006285	C	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006285	P	Seeded From UniProt	complete
enables	GO:0008641	ubiquitin-like modifier activating enzyme activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000594 InterPro:IPR035985	F	Seeded From UniProt	complete
involved_in	GO:0006914	autophagy	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0072	P	Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P	Seeded From UniProt	complete
part_of	GO:0000407	phagophore assembly site	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0220	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Radoshevich, L et al. (2010) ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Cell 142 590-600 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:20723759-1] Radoshevich, L et al. (2010) ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Cell 142 590-600 PubMed GONUTS page

[PMID:21873635-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:ATG7

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