CHICK:ARF6

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	ARF6 (synonyms: CPS1)
Protein Name(s)	ADP-ribosylation factor 6
External Links
UniProt	P26990
EMBL	X03682
PIR	I50632
RefSeq	NP_001075174.1
UniGene	Gga.2511
ProteinModelPortal	P26990
SMR	P26990
IntAct	P26990
MINT	MINT-6824981
PRIDE	P26990
GeneID	428927
KEGG	gga:428927
CTD	382
HOVERGEN	HBG002073
InParanoid	P26990
KO	K07941
PhylomeDB	P26990
NextBio	20829803
PRO	PR:P26990
Proteomes	UP000000539
ExpressionAtlas	P26990
GO	GO:0005938 GO:0005737 GO:0030139 GO:0005768 GO:0070062 GO:0031527 GO:0005925 GO:0005794 GO:0043209 GO:0005886 GO:0055038 GO:0001726 GO:0005525 GO:0030866 GO:0090162 GO:0097284 GO:0001889 GO:0033028 GO:0030838 GO:0090004 GO:0034394 GO:0036010 GO:0015031 GO:0060998 GO:0051489 GO:0035020 GO:0031529 GO:0007264 GO:0016192
Gene3D	3.40.50.300
InterPro	IPR027417 IPR005225 IPR024156 IPR006689
Pfam	PF00025
PRINTS	PR00328
SMART	SM00177
SUPFAM	SSF52540
TIGRFAMs	TIGR00231
PROSITE	PS51417

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0032587	ruffle membrane	PMID:10934473^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:10934473^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0035020	regulation of Rac protein signal transduction	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	P	Seeded From UniProt	complete
involved_in	GO:0097178	ruffle assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	P	Seeded From UniProt	complete
involved_in	GO:0030866	cortical actin cytoskeleton organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	P	Seeded From UniProt	complete
involved_in	GO:0030838	positive regulation of actin filament polymerization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	P	Seeded From UniProt	complete
part_of	GO:0005938	cell cortex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62331	C	Seeded From UniProt	complete
part_of	GO:0001726	ruffle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	C	Seeded From UniProt	complete
part_of	GO:0030139	endocytic vesicle	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P62330	C	Seeded From UniProt	complete
involved_in	GO:0060998	regulation of dendritic spine development	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99435 PANTHER:PTN000195685 RGD:621279	P	Seeded From UniProt	complete
part_of	GO:0055038	recycling endosome membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000195685 UniProtKB:P62330	C	Seeded From UniProt	complete
involved_in	GO:0036010	protein localization to endosome	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99435 PANTHER:PTN000195685 UniProtKB:P62330	P	Seeded From UniProt	complete
part_of	GO:0030139	endocytic vesicle	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000195685 UniProtKB:P62330	C	Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99431 PANTHER:PTN000918181 SGD:S000000368 UniProtKB:P51823	P	Seeded From UniProt	complete
involved_in	GO:0006886	intracellular protein transport	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000918181 UniProtKB:P51823 WB:WBGene00000182	P	Seeded From UniProt	complete
part_of	GO:0005768	endosome	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99435 PANTHER:PTN000195685 UniProtKB:P62330	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010348 MGI:MGI:1927136 MGI:MGI:1933161 MGI:MGI:99433 MGI:MGI:99434 MGI:MGI:99435 MGI:MGI:99436 PANTHER:PTN000917851 UniProtKB:P26990 UniProtKB:P49703 UniProtKB:P56559	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000115 MGI:MGI:99431 PANTHER:PTN000917851 RGD:621270 RGD:621587 UniProtKB:P18085 UniProtKB:P36406 UniProtKB:P40616 UniProtKB:P40617 UniProtKB:Q7KQL3 dictyBase:DDB_G0289173	F	Seeded From UniProt	complete
part_of	GO:0001726	ruffle	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000195685 RGD:621279 UniProtKB:P62330	C	Seeded From UniProt	complete
involved_in	GO:2000009	negative regulation of protein localization to cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:1903393	positive regulation of adherens junction organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:1903078	positive regulation of protein localization to plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0097284	hepatocyte apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0090162	establishment of epithelial cell polarity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0060998	regulation of dendritic spine development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0051549	positive regulation of keratinocyte migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	F	Seeded From UniProt	complete
involved_in	GO:0036010	protein localization to endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0034394	protein localization to cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0033028	myeloid cell apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0010975	regulation of neuron projection development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	C	Seeded From UniProt	complete
involved_in	GO:0001889	liver development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62331 ensembl:ENSMUSP00000055862	P	Seeded From UniProt	complete
involved_in	GO:0097178	ruffle assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
part_of	GO:0090543	Flemming body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
part_of	GO:0055038	recycling endosome membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
involved_in	GO:0051489	regulation of filopodium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
involved_in	GO:0036010	protein localization to endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
involved_in	GO:0035020	regulation of Rac protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
involved_in	GO:0032456	endocytic recycling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
part_of	GO:0032154	cleavage furrow	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
enables	GO:0031996	thioesterase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	F	Seeded From UniProt	complete
part_of	GO:0031527	filopodium membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
involved_in	GO:0030866	cortical actin cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
involved_in	GO:0030838	positive regulation of actin filament polymerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	P	Seeded From UniProt	complete
part_of	GO:0030139	endocytic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
part_of	GO:0005938	cell cortex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
part_of	GO:0001726	ruffle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P62330 ensembl:ENSP00000298316	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR005225 InterPro:IPR006689	F	Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P	Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C	Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F	Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C	Seeded From UniProt	complete
part_of	GO:0031527	filopodium membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0287	C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0091	C	Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0100	C	Seeded From UniProt	complete
part_of	GO:0001726	ruffle	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0300	C	Seeded From UniProt	complete
part_of	GO:0090543	Flemming body	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0490	C	Seeded From UniProt	complete
part_of	GO:0055038	recycling endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0231	C	Seeded From UniProt	complete
part_of	GO:0032154	cleavage furrow	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0467	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Di Cesare, A et al. (2000) p95-APP1 links membrane transport to Rac-mediated reorganization of actin. Nat. Cell Biol. 2 521-30 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 ^2.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10934473-1] 1.0 ^1.1 Di Cesare, A et al. (2000) p95-APP1 links membrane transport to Rac-mediated reorganization of actin. Nat. Cell Biol. 2 521-30 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 ^2.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:ARF6

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Annotations

Notes

References

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