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CHICK:ACTN2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ACTN2
Protein Name(s) Alpha-actinin-2

Alpha-actinin skeletal muscle isoform 2 F-actin cross-linking protein

External Links
UniProt P20111
EMBL X13874
X59247
X68797
X68798
X68799
X68800
X68801
X68802
PIR S02032
RefSeq NP_990654.1
UniGene Gga.4843
ProteinModelPortal P20111
SMR P20111
STRING 9031.ENSGALP00000023309
PaxDb P20111
PRIDE P20111
GeneID 396263
KEGG gga:396263
CTD 88
eggNOG COG5069
HOGENOM HOG000263418
HOVERGEN HBG050453
InParanoid P20111
KO K05699
OrthoDB EOG72C4ZJ
PhylomeDB P20111
TreeFam TF352676
Reactome REACT_288861
REACT_300222
REACT_303305
REACT_318735
REACT_335363
NextBio 20816315
PRO PR:P20111
Proteomes UP000000539
ExpressionAtlas P20111
GO GO:0070062
GO:0030175
GO:0005925
GO:0030018
GO:0005509
GO:0030375
GO:0048041
GO:0030035
GO:0006936
GO:1901017
GO:2000009
GO:1901018
GO:0051289
GO:0042391
Gene3D 1.10.238.10
1.10.418.10
InterPro IPR001589
IPR001715
IPR011992
IPR014837
IPR002048
IPR018159
IPR002017
Pfam PF00307
PF08726
PF00435
SMART SM00033
SM00054
SM00150
SUPFAM SSF47576
PROSITE PS00019
PS00020
PS50021
PS50222

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0030175

filopodium

PMID:12356918[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0030035

microspike assembly

PMID:12356918[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9JI91

C

Seeded From UniProt

complete

part_of

GO:0097381

photoreceptor disc membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

C

Seeded From UniProt

complete

enables

GO:0045505

dynein intermediate chain binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

F

Seeded From UniProt

complete

enables

GO:0034452

dynactin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

F

Seeded From UniProt

complete

part_of

GO:0032391

photoreceptor connecting cilium

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

C

Seeded From UniProt

complete

enables

GO:0032029

myosin tail binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

F

Seeded From UniProt

complete

part_of

GO:0031941

filamentous actin

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1921642
PANTHER:PTN001141409

C

Seeded From UniProt

complete

enables

GO:0030507

spectrin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

F

Seeded From UniProt

complete

involved_in

GO:0030036

actin cytoskeleton organization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1921642
PANTHER:PTN001141409

P

Seeded From UniProt

complete

enables

GO:0019894

kinesin binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

F

Seeded From UniProt

complete

involved_in

GO:0007041

lysosomal transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

P

Seeded From UniProt

complete

involved_in

GO:0007030

Golgi organization

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

P

Seeded From UniProt

complete

part_of

GO:0005815

microtubule organizing center

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1921642
PANTHER:PTN001141409

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000936880
UniProtKB:Q9NRC6

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002048

F

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0314

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Guvakova, MA et al. (2002) Functional role of alpha-actinin, PI 3-kinase and MEK1/2 in insulin-like growth factor I receptor kinase regulated motility of human breast carcinoma cells. J. Cell. Sci. 115 4149-65 PubMed GONUTS page
  2. 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page