GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

CHICK:ACCN2

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) ACCN2 (synonyms: ASIC1)
Protein Name(s) Amiloride-sensitive cation channel 2, neuronal

Acid-sensing ion channel 1

External Links
UniProt Q1XA76
EMBL AY956393
IPI IPI00588169
RefSeq NP_001035557.1
UniGene Gga.17954
PDB 2QTS
3HGC
3IJ4
PDBsum 2QTS
3HGC
3IJ4
ProteinModelPortal Q1XA76
SMR Q1XA76
DIP DIP-59283N
TCDB 1.A.6.1.5
GeneID 426883
KEGG gga:426883
CTD 41
eggNOG NOG262945
HOVERGEN HBG004150
KO K04829
EvolutionaryTrace Q1XA76
NextBio 20828282
GO GO:0016021
GO:0005886
GO:0015280
InterPro IPR004724
IPR001873
IPR020903
PANTHER PTHR11690
Pfam PF00858
PRINTS PR01078
TIGRFAMs TIGR00859
PROSITE PS01206

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071467

cellular response to pH

PMID:17882215[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0070207

protein homotrimerization

PMID:17882215[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0044736

acid-sensing ion channel activity

PMID:17882215[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0035725

sodium ion transmembrane transport

PMID:17882215[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:17882215[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:22842900[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q1XA76

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:19641589[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q1XA76

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:17882215[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q1XA76

F

Seeded From UniProt

complete

enables

GO:0005272

sodium channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001873
InterPro:IPR020903

F

Seeded From UniProt

complete

involved_in

GO:0006814

sodium ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001873
InterPro:IPR004724
InterPro:IPR020903

P

Seeded From UniProt

complete

enables

GO:0015280

ligand-gated sodium channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004724

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001873
InterPro:IPR020903

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004724

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

involved_in

GO:0006814

sodium ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0739

P

Seeded From UniProt

complete

enables

GO:0005272

sodium channel activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0894

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Jasti, J et al. (2007) Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. Nature 449 316-23 PubMed GONUTS page
  2. Baconguis, I & Gouaux, E (2012) Structural plasticity and dynamic selectivity of acid-sensing ion channel-spider toxin complexes. Nature 489 400-5 PubMed GONUTS page
  3. Gonzales, EB et al. (2009) Pore architecture and ion sites in acid-sensing ion channels and P2X receptors. Nature 460 599-604 PubMed GONUTS page