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CHICK:AATM

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) GOT2
Protein Name(s) Aspartate aminotransferase, mitochondrial

mAspAT Glutamate oxaloacetate transaminase 2 Kynurenine aminotransferase 4 Kynurenine aminotransferase IV Kynurenine--oxoglutarate transaminase 4 Kynurenine--oxoglutarate transaminase IV Transaminase A

External Links
UniProt P00508
EMBL M12105
PIR A24554
RefSeq NP_990854.1
UniGene Gga.4425
PDB 1AKA
1AKB
1AKC
1AMA
1IVR
1MAP
1MAQ
1OXO
1OXP
1TAR
1TAS
1TAT
7AAT
8AAT
9AAT
PDBsum 1AKA
1AKB
1AKC
1AMA
1IVR
1MAP
1MAQ
1OXO
1OXP
1TAR
1TAS
1TAT
7AAT
8AAT
9AAT
ProteinModelPortal P00508
SMR P00508
BioGrid 676777
IntAct P00508
STRING 9031.ENSGALP00000003646
PaxDb P00508
PRIDE P00508
GeneID 396533
KEGG gga:396533
CTD 2806
eggNOG COG1448
HOGENOM HOG000185898
HOVERGEN HBG000951
InParanoid P00508
KO K14455
PhylomeDB P00508
Reactome REACT_115534
REACT_116093
EvolutionaryTrace P00508
NextBio 20816569
PRO PR:P00508
Proteomes UP000000539
GO GO:0005759
GO:0005739
GO:0016212
GO:0004069
GO:0080130
GO:0042803
GO:0030170
GO:0006103
GO:0006531
GO:0005975
GO:0006520
GO:0006094
GO:0006536
GO:0044281
Gene3D 3.40.640.10
InterPro IPR004839
IPR000796
IPR004838
IPR015424
IPR015421
PANTHER PTHR11879
Pfam PF00155
PRINTS PR00799
SUPFAM SSF53383
PROSITE PS00105

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042803

protein homodimerization activity

PMID:8665890[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P00508

F

Seeded From UniProt

complete

involved_in

GO:0006536

glutamate metabolic process

PMID:8665890[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006531

aspartate metabolic process

PMID:8665890[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006103

2-oxoglutarate metabolic process

PMID:8665890[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:8665890[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

PMID:8665890[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006533

aspartate catabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000222759
UniProtKB:P00505

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95792
PANTHER:PTN000222845
RGD:2722
SGD:S000001589
UniProtKB:P00505
UniProtKB:P00508

C

Seeded From UniProt

complete

enables

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001125
MGI:MGI:95792
PANTHER:PTN000222845
RGD:2722
UniProtKB:P00505
UniProtKB:P00508

F

Seeded From UniProt

complete

involved_in

GO:0097052

L-kynurenine metabolic process

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016212

P

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004838
InterPro:IPR015421
InterPro:IPR015422

F

Seeded From UniProt

complete

involved_in

GO:0006520

cellular amino acid metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000796

P

Seeded From UniProt

complete

enables

GO:0008483

transaminase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000796

F

Seeded From UniProt

complete

involved_in

GO:0009058

biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004838
InterPro:IPR004839

P

Seeded From UniProt

complete

enables

GO:0030170

pyridoxal phosphate binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004838
InterPro:IPR004839

F

Seeded From UniProt

complete

enables

GO:0016212

kynurenine-oxoglutarate transaminase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.6.1.7

F

Seeded From UniProt

complete

enables

GO:0004069

L-aspartate:2-oxoglutarate aminotransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.6.1.1

F

Seeded From UniProt

complete

involved_in

GO:0006520

cellular amino acid metabolic process

Reactome:R-GGA-372568

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006094

gluconeogenesis

Reactome:R-GGA-352875

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

Reactome:R-GGA-372564
Reactome:R-GGA-372559

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0008483

transaminase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0032

F

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0170

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Marković-Housley, Z et al. (1996) Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase. Eur. J. Biochem. 236 1025-32 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page