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CHICK:A1EAT1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CHEK2 (ECO:0000313 with EMBL:ABL14109.1)
Protein Name(s) Checkpoint and tumor suppressor protein 2 (ECO:0000313 with EMBL:ABL14109.1)
External Links
UniProt A1EAT1
EMBL EF118300
RefSeq NP_001073576.1
UniGene Gga.2517
ProteinModelPortal A1EAT1
SMR A1EAT1
STRING 9031.ENSGALP00000009122
PaxDb A1EAT1
GeneID 768913
KEGG gga:768913
CTD 11200
eggNOG COG0515
HOGENOM HOG000233016
HOVERGEN HBG108055
KO K06641
PhylomeDB A1EAT1
Reactome REACT_115715
REACT_239259
REACT_263750
NextBio 20919157
ExpressionAtlas A1EAT1
GO GO:0000781
GO:0005654
GO:0016605
GO:0005524
GO:0004674
GO:0044257
GO:0006975
GO:0006281
GO:0006302
GO:0000724
GO:0000086
GO:0008630
GO:0045893
GO:0046777
GO:0050821
GO:0042176
GO:0010332
GO:0072428
GO:0090307
Gene3D 2.60.200.20
InterPro IPR000253
IPR011009
IPR000719
IPR002290
IPR008271
IPR008984
Pfam PF00498
PF00069
SMART SM00240
SM00220
SUPFAM SSF49879
SSF56112
PROSITE PS50006
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

F

complete

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

complete

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

F

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

F

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002290

P

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

P

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017442

P

complete

GO:0010332

response to gamma radiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000066679

P

complete

GO:0042770

signal transduction in response to DNA damage

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000066679

P

complete

GO:0000086

G2/M transition of mitotic cell cycle

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0000724

double-strand break repair via homologous recombination

Reactome:REACT_115651

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0000724

double-strand break repair via homologous recombination

Reactome:REACT_115715

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0000724

double-strand break repair via homologous recombination

Reactome:REACT_115769

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0000724

double-strand break repair via homologous recombination

Reactome:REACT_115936

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0000781

chromosome, telomeric region

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

C

Seeded From UniProt

complete

GO:0001302

replicative cell aging

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0004672

protein kinase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290
InterPro:IPR008271

F

Seeded From UniProt

complete

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

F

Seeded From UniProt

complete

GO:0005524

ATP binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

Seeded From UniProt

complete

GO:0005654

nucleoplasm

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

C

Seeded From UniProt

complete

GO:0005654

nucleoplasm

Reactome:REACT_116016

TAS: Traceable Author Statement

C

Seeded From UniProt

complete

GO:0005794

Golgi apparatus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

C

Seeded From UniProt

complete

GO:0006281

DNA repair

Reactome:REACT_115642

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0006302

double-strand break repair

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0006302

double-strand break repair

Reactome:REACT_116061

TAS: Traceable Author Statement

P

Seeded From UniProt

complete

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0006468

protein phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290
InterPro:IPR008271

P

Seeded From UniProt

complete

GO:0006915

apoptotic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000066679

P

Seeded From UniProt

complete

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0006975

DNA damage induced protein phosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0008630

intrinsic apoptotic signaling pathway in response to DNA damage

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0010332

response to gamma radiation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSMUSP00000066679

P

Seeded From UniProt

complete

GO:0016605

PML body

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

C

Seeded From UniProt

complete

GO:0019901

protein kinase binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

F

Seeded From UniProt

complete

GO:0031625

ubiquitin protein ligase binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

F

Seeded From UniProt

complete

GO:0042176

regulation of protein catabolic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0042770

signal transduction in response to DNA damage

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0042802

identical protein binding

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

F

Seeded From UniProt

complete

GO:0042803

protein homodimerization activity

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

F

Seeded From UniProt

complete

GO:0044257

cellular protein catabolic process

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0046777

protein autophosphorylation

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0050821

protein stabilization

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0072428

signal transduction involved in intra-S DNA damage checkpoint

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

GO:0090307

mitotic spindle assembly

GO_REF:0000019

IEA: Inferred from Electronic Annotation

Ensembl:ENSP00000372023

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.