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CAUVC:PLED

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Species (Taxon ID) Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobactercrescentus). (190650)
Gene Name(s) pleD
Protein Name(s) Response regulator PleD

Stalked cell differentiation-controlling protein Diguanylate cyclase DGC Diguanylate kinase

External Links
UniProt Q9A5I5
EMBL L42554
AE005673
PIR E87554
RefSeq NP_421265.1
WP_010920320.1
ProteinModelPortal Q9A5I5
SMR Q9A5I5
DIP DIP-29503N
IntAct Q9A5I5
STRING 190650.CC_2462
DrugBank DB01972
EnsemblBacteria AAK24433
GeneID 943650
KEGG ccr:CC_2462
PATRIC fig|190650.5.peg.2479
eggNOG ENOG4105BZU
ENOG410XNMH
HOGENOM HOG000167204
KO K02488
OMA NDYFVYP
BioCyc CAULO:CC2462-MONOMER
BRENDA 2.7.7.65
UniPathway UPA00599
Proteomes UP000001816
GO GO:0005737
GO:0052621
GO:0005525
GO:0042802
GO:0046872
GO:0007049
GO:0030154
GO:0000160
CDD cd01949
cd00156
InterPro IPR011006
IPR000160
IPR029787
IPR001789
Pfam PF00990
PF00072
SMART SM00267
SM00448
SUPFAM SSF52172
SSF55073
TIGRFAMs TIGR00254
PROSITE PS50887
PS50110

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042802

identical protein binding

PMID:18455986[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9A5I5

F

Seeded From UniProt

enables

GO:0042802

identical protein binding

PMID:17697997[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9A5I5

F

Seeded From UniProt

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

enables

GO:0052621

diguanylate cyclase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.65

F

Seeded From UniProt

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

enables

GO:0042802

identical protein binding

PMID:18455986[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9A5I5

F

Seeded From UniProt

enables

GO:0042802

identical protein binding

PMID:17697997[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9A5I5

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:18455986[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q03228

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:18455986[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P37894

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:16176121[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q03228

F

Seeded From UniProt

enables

GO:0005515

protein binding

PMID:16176121[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P37894

F

Seeded From UniProt

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

enables

GO:0052621

diguanylate cyclase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.65

F

Seeded From UniProt

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

part_of

GO:0005737

cytoplasm

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

GO:0000160

phosphorelay signal transduction system

PMID:16176121[3]

ECO:0001202

P

Figure 5 displays the phosphotransfer profiling of Caulobacter crescentus and shows that the response regulator pleD is selectively phosphorylated by the histidine kinase pleC.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Paul, R et al. (2008) Allosteric regulation of histidine kinases by their cognate response regulator determines cell fate. Cell 133 452-61 PubMed GONUTS page
  2. 2.0 2.1 Wassmann, P et al. (2007) Structure of BeF3- -modified response regulator PleD: implications for diguanylate cyclase activation, catalysis, and feedback inhibition. Structure 15 915-27 PubMed GONUTS page
  3. 3.0 3.1 3.2 Skerker, JM et al. (2005) Two-component signal transduction pathways regulating growth and cell cycle progression in a bacterium: a system-level analysis. PLoS Biol. 3 e334 PubMed GONUTS page