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CAUCN:B8H389

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Species (Taxon ID) Caulobacter crescentus (strain NA1000 / CB15N). (565050)
Gene Name(s) xylR (ECO:0000313 with EMBL:ACL96626.1)
Protein Name(s) Transcriptional regulator xylR (ECO:0000313 with EMBL:ACL96626.1)
External Links
UniProt B8H389
EMBL CP001340
RefSeq YP_002518534.1
ProteinModelPortal B8H389
SMR B8H389
STRING 190650.CC_3065
EnsemblBacteria ACL96626
GeneID 7330999
KEGG ccs:CCNA_03161
PATRIC 21310831
eggNOG COG1609
HOGENOM HOG000220179
KO K02529
OMA YQIINAE
OrthoDB EOG6SJJMM
BioCyc CAULONA1000:CCNA_03161-MONOMER
Proteomes UP000001364
GO GO:0003677
GO:0003700
GO:0006351
Gene3D 1.10.260.40
InterPro IPR010982
IPR028082
IPR000843
Pfam PF00356
PRINTS PR00036
SMART SM00354
SUPFAM SSF47413
SSF53822
PROSITE PS00356
PS50932

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006355

regulation of transcription, DNA-dependent

PMID:17933895[1]

ECO:0000314

P

Figure 3 shows that in the absence of D-xylose, XylR binds to operator sites overlapping promoters of xylose-inducible genes, preventing initiation of transcription by RNA polymerase. When d-xylose is present, it binds to XylR, stabilizing a conformation with greatly reduced affinity for DNA and freeing xylose-inducible promoters for expression.

complete

GO:0003677

DNA binding

PMID:17933895[1]

ECO:0000314

F

Figure 3B shows a gel mobility shift assay displaying XylR-DNA complexes, therefore this shows that xylR can bind to DNA.

complete

GO:0005622

intracellular

PMID:17933895[1]

ECO:0000314

C

Figure 3 shows residual xylR-DNA complexes via a gel mobility shift assay in vitro and since DNA is located in the nucleus, this proves that the protein xylR is intracellular.

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000843
InterPro:IPR010982

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000843

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

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  1. 1.0 1.1 1.2 Stephens, C et al. (2007) Regulation of D-xylose metabolism in Caulobacter crescentus by a LacI-type repressor. J. Bacteriol. 189 8828-34 PubMed GONUTS page