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CANFA:AP3B1
Contents
Species (Taxon ID) | Canis familiaris (Dog) (Canis lupus familiaris). (9615) | |
Gene Name(s) | AP3B1 (synonyms: ADTB3A) | |
Protein Name(s) | AP-3 complex subunit beta-1
Adaptor protein complex AP-3 subunit beta-1 Adaptor-related protein complex 3 subunit beta-1 Beta-3A-adaptin Clathrin assembly protein complex 3 beta-1 large chain | |
External Links | ||
UniProt | Q7YRF1 | |
EMBL | AY221640 | |
RefSeq | NP_001002974.1 | |
UniGene | Cfa.169 | |
ProteinModelPortal | Q7YRF1 | |
STRING | 9615.ENSCAFP00000013540 | |
PRIDE | Q7YRF1 | |
GeneID | 403459 | |
KEGG | cfa:403459 | |
CTD | 8546 | |
eggNOG | COG5096 | |
HOGENOM | HOG000033978 | |
HOVERGEN | HBG050519 | |
InParanoid | Q7YRF1 | |
KO | K12397 | |
NextBio | 20816977 | |
Proteomes | UP000002254 | |
GO | GO:0030123 GO:0030665 GO:0005794 GO:0008089 GO:0048490 GO:0006886 | |
Gene3D | 1.25.10.10 | |
InterPro | IPR026740 IPR029394 IPR029390 IPR026739 IPR011989 IPR016024 IPR002553 | |
PANTHER | PTHR11134 | |
Pfam | PF01602 PF14796 PF14797 | |
PIRSF | PIRSF037096 | |
SUPFAM | SSF48371 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
Contributes to |
GO:0061082 |
myeloid leukocyte cytokine production |
ECO:0000315 |
P |
Figure 1 shows that a mutation of AP3B1 causes canine cyclic hematopoiesis, which results in reciprocal cycles of leukocyte (neutrophil and monocyte) production. |
complete | ||||
Contributes to |
GO:0043473 |
pigmentation |
ECO:0000315 |
P |
Table 1 shows that a mutation of AP3B1 causes canine cyclic hematopoiesis which results in gray coat color in dogs. |
complete | ||||
involved_in |
GO:0048490 |
anterograde synaptic vesicle transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008089 |
anterograde axonal transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:1904115 |
axon cytoplasm |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0008089 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006886 |
intracellular protein transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002553 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0030117 |
membrane coat |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030123 |
AP-3 adaptor complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030131 |
clathrin adaptor complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030665 |
clathrin-coated vesicle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Benson, KF et al. (2003) Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase. Nat. Genet. 35 90-6 PubMed GONUTS page
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