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CAEEL:SPE9

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) spe-9
Protein Name(s) Sperm transmembrane protein 9

Fertilization defective 9 Spermatogenesis defective 9

External Links
UniProt Q9TVY6
EMBL AF049327
Z81473
Z81063
Z81473
Z81063
AF492686
AF492687
AF492688
AF492690
AF492691
AF492692
AF492693
AF492694
AF492695
AF492696
AF492697
AF492698
AF492699
AF492700
AF492701
PIR T42754
RefSeq NP_001129750.1
NP_492955.1
UniGene Cel.19642
ProteinModelPortal Q9TVY6
SMR Q9TVY6
STRING 6239.C17D12.6a
PaxDb Q9TVY6
EnsemblMetazoa C17D12.6a
GeneID 173042
KEGG cel:CELE_C17D12.6
UCSC C17D12.6
CTD 173042
WormBase C17D12.6a
C17D12.6b
eggNOG NOG304855
InParanoid Q9TVY6
OrthoDB EOG7K6PZP
PhylomeDB Q9TVY6
NextBio 878031
Proteomes UP000001940
GO GO:0009986
GO:0005737
GO:0016021
GO:0043227
GO:0005886
GO:0031143
GO:0005102
GO:0007155
GO:0007338
InterPro IPR000742
IPR013032
SMART SM00181
PROSITE PS00022
PS01186
PS50026

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009566

fertilization

PMID:9546393[1]

ECO:0000315

P

This paper describes mutant SPE-9 deficient nematode spermatozoa that were unable to fertilize normal egg cells preventing egg fertilization. Figure 1 shows a graphical representation of the infertility and ovulation of SPE-9 mutant nematodes. Figure 2 and Figure 3 show microscope images of mutant spermatozoa cells

complete
CACAO 4929

part_of

GO:0043227

membrane-bounded organelle

PMID:15282160[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031143

pseudopodium

PMID:15282160[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:15282160[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007338

single fertilization

PMID:9546393[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:9546393[1]

ECO:0000250

sequence similarity evidence used in manual assertion

C

Seeded From UniProt

Missing: with/from

part_of

GO:0005737

cytoplasm

PMID:15282160[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

PMID:9546393[1]

ECO:0000250

sequence similarity evidence used in manual assertion

F

Seeded From UniProt

Missing: with/from

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001881

F

Seeded From UniProt

complete

involved_in

GO:0007338

single fertilization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0278

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Singson, A et al. (1998) The C. elegans spe-9 gene encodes a sperm transmembrane protein that contains EGF-like repeats and is required for fertilization. Cell 93 71-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Putiri, E et al. (2004) Functional domains and temperature-sensitive mutations in SPE-9, an EGF repeat-containing protein required for fertility in Caenorhabditis elegans. Dev. Biol. 272 448-59 PubMed GONUTS page