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CAEEL:Q6Q762

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) nca-1 (ECO:0000313 with EMBL:AAS65871.2)
Protein Name(s) Four domain-type voltage-gated ion channel alpha-1 subunit (ECO:0000313 with EMBL:AAS65871.2)
External Links
UniProt Q6Q762
EMBL AY555271
ProteinModelPortal Q6Q762
UCSC C11D2.6d
Reactome REACT_197702
ExpressionAtlas Q6Q762
GO GO:0016021
GO:0005244
Gene3D 1.20.120.350
InterPro IPR027359
IPR005821
Pfam PF00520

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019227

neuronal action potential propagation

PMID:18336069[1]

IMP: Inferred from Mutant Phenotype

P

Fig. 2: NCA-1 required for normal synaptic transmission

Fig. 4: antibody staining of NCA-1 reveals punctate staining along nerve ring and nerve chord without colocalization w/ presynaptic proteins that was absent in mutant

complete
CACAO 6773

GO:0005216

ion channel activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

F

Seeded From UniProt

complete

GO:0005244

voltage-gated ion channel activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0851

F

Seeded From UniProt

complete

GO:0006810

transport

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

Seeded From UniProt

complete

GO:0006811

ion transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

complete

GO:0006811

ion transport

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

C

Seeded From UniProt

complete

GO:0016020

membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0019227

neuronal action potential propagation

PMID:18336069[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0034220

ion transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

complete

GO:0034765

regulation of ion transmembrane transport

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0851

P

Seeded From UniProt

complete

GO:0055085

transmembrane transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005821

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Yeh, E et al. (2008) A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans. PLoS Biol. 6 e55 PubMed GONUTS page