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CAEEL:Q23192

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) atat-2
Protein Name(s) Alpha-tubulin N-acetyltransferase 2 (ECO:0000255 with HAMAP-Rule:MF_03130)

Alpha-TAT 2 (ECO:0000255 with HAMAP-Rule:MF_03130) TAT 2 (ECO:0000255 with HAMAP-Rule:MF_03130) Mec-17 like protein

External Links
UniProt Q23192
EMBL FO081143
PIR T26219
RefSeq NP_508981.1
UniGene Cel.19790
ProteinModelPortal Q23192
SMR Q23192
BioGrid 45785
DIP DIP-26342N
MINT MINT-1119863
STRING 6239.W06B11.1
PaxDb Q23192
PRIDE Q23192
EnsemblMetazoa W06B11.1
GeneID 180852
KEGG cel:CELE_W06B11.1
UCSC W06B11.1
CTD 180852
WormBase W06B11.1
eggNOG NOG249793
GeneTree ENSGT00390000008276
HOGENOM HOG000020401
InParanoid Q23192
OMA NTSPIGR
OrthoDB EOG7MH105
PhylomeDB Q23192
NextBio 911262
Proteomes UP000001940
GO GO:0004468
GO:0019799
GO:0071929
GO:0048666
GO:0006473
GO:0070507
GO:0001966
HAMAP MF_03130
InterPro IPR007965
PANTHER PTHR12327
Pfam PF05301
PROSITE PS51730

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019799

tubulin N-acetyltransferase activity

PMID:20829795[1]

IGI: Inferred from Genetic Interaction

UniProtKB:O45100


F

Figure 2 shows that this gene, along with mec-17, regulated the acetylation of alpha tubulin (as determined by antibody 6-11B-1

complete
CACAO 3599

GO:0001966

thigmotaxis

PMID:20829795[1]

IGI: Inferred from Genetic Interaction

P

Missing: with/from

GO:0006473

protein acetylation

PMID:20829795[1]

IGI: Inferred from Genetic Interaction

P

Missing: with/from

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

complete

GO:0019799

tubulin N-acetyltransferase activity

PMID:20829795[1]

IMP: Inferred from Mutant Phenotype

F

complete

GO:0001966

thigmotaxis

PMID:20829795[1]

IGI: Inferred from Genetic Interaction

WB:WBGene00003178

P

Seeded From UniProt

complete

GO:0001966

thigmotaxis

PMID:20829795[1]

IMP: Inferred from Mutant Phenotype

WB:WBVar00093564

P

Seeded From UniProt

complete

GO:0001966

thigmotaxis

PMID:24846647[2]

IGI: Inferred from Genetic Interaction

WB:WBGene00003178

P

Seeded From UniProt

complete

GO:0001966

thigmotaxis

PMID:24846647[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0004468

lysine N-acetyltransferase activity, acting on acetyl phosphate as donor

PMID:20829795[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q22XZ3

F

Seeded From UniProt

complete

GO:0005575

cellular_component

GO_REF:0000015

ND: No biological Data available

C

Seeded From UniProt

complete

GO:0005874

microtubule

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007965

C

Seeded From UniProt

complete

GO:0006473

protein acetylation

PMID:20829795[1]

IGI: Inferred from Genetic Interaction

WB:WBGene00003178

P

Seeded From UniProt

complete

GO:0016740

transferase activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03130

F

Seeded From UniProt

complete

GO:0016740

transferase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

GO:0019799

tubulin N-acetyltransferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007965

F

Seeded From UniProt

complete

GO:0019799

tubulin N-acetyltransferase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.3.1.108

F

Seeded From UniProt

complete

GO:0019799

tubulin N-acetyltransferase activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03130

F

Seeded From UniProt

complete

GO:0019799

tubulin N-acetyltransferase activity

PMID:20829795[1]

IMP: Inferred from Mutant Phenotype

F

Seeded From UniProt

complete

GO:0048666

neuron development

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03130

P

Seeded From UniProt

complete

GO:0070507

regulation of microtubule cytoskeleton organization

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03130

P

Seeded From UniProt

complete

GO:0071929

alpha-tubulin acetylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007965

P

Seeded From UniProt

complete

GO:0071929

alpha-tubulin acetylation

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_03130

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Akella, JS et al. (2010) MEC-17 is an alpha-tubulin acetyltransferase. Nature 467 218-22 PubMed GONUTS page
  2. 2.0 2.1 Davenport, AM et al. (2014) Structural and functional characterization of the α-tubulin acetyltransferase MEC-17. J. Mol. Biol. 426 2605-16 PubMed GONUTS page