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CAEEL:ILB3

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) ins-3
Protein Name(s) Probable insulin-like peptide beta-type 3
External Links
UniProt Q09628
EMBL FO080104
PIR T27988
RefSeq NP_495195.1
UniGene Cel.14852
ProteinModelPortal Q09628
SMR Q09628
STRING 6239.ZK75.3
PaxDb Q09628
EnsemblMetazoa ZK75.3
GeneID 191684
KEGG cel:CELE_ZK75.3
UCSC ZK75.3
CTD 191684
WormBase ZK75.3
eggNOG ENOG410K7UB
ENOG4110M2A
HOGENOM HOG000016980
InParanoid Q09628
OMA CCETMCT
OrthoDB EOG091G13ZG
PhylomeDB Q09628
PRO PR:Q09628
Proteomes UP000001940
Bgee WBGene00002086
GO GO:0005576
InterPro IPR016179
IPR022353
IPR003235
Pfam PF03488
SUPFAM SSF56994
PROSITE PS00262

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0047484

regulation of response to osmotic stress

PMID:28166192[1]

ECO:0000315

P

Supplementary Figs. 1h and 1i: Shows that INS-3 is responsible for developmental arrest in response to osmotic stress. Referred to in paper as INS-3, insulin like peptide, in C. elegans.

complete
CACAO 12274

involved_in

GO:1905910

negative regulation of dauer entry

PMID:24671950[2]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:Q9NEK7

P

Seeded From UniProt

complete

involved_in

GO:0040024

dauer larval development

PMID:23665919[3]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:Q18223,UniProtKB:Q9NEK7

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005179

P

Seeded From UniProt

complete

enables

GO:0005179

hormone activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003235

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003235

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Burton, NO et al. (2017) Insulin-like signalling to the maternal germline controls progeny response to osmotic stress. Nat. Cell Biol. PubMed GONUTS page
  2. Hung, WL et al. (2014) A Caenorhabditis elegans developmental decision requires insulin signaling-mediated neuron-intestine communication. Development 141 1767-79 PubMed GONUTS page
  3. Hung, WL et al. (2013) Attenuation of insulin signalling contributes to FSN-1-mediated regulation of synapse development. EMBO J. 32 1745-60 PubMed GONUTS page