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CAEEL:GRK2
Contents
| Species (Taxon ID) | Caenorhabditis elegans. (6239) | |
| Gene Name(s) | grk-2 | |
| Protein Name(s) | G protein-coupled receptor kinase 2 | |
| External Links | ||
| UniProt | Q09639 | |
| EMBL | FO080476 | |
| PIR | T26096 | |
| RefSeq | NP_497235.2 | |
| UniGene | Cel.9949 | |
| ProteinModelPortal | Q09639 | |
| SMR | Q09639 | |
| IntAct | Q09639 | |
| MINT | MINT-1795241 | |
| STRING | 6239.W02B3.2 | |
| PaxDb | Q09639 | |
| PRIDE | Q09639 | |
| EnsemblMetazoa | W02B3.2 | |
| GeneID | 175223 | |
| KEGG | cel:CELE_W02B3.2 | |
| UCSC | W02B3.2 | |
| CTD | 175223 | |
| WormBase | W02B3.2 | |
| eggNOG | COG0515 | |
| GeneTree | ENSGT00770000120493 | |
| HOGENOM | HOG000006742 | |
| InParanoid | Q09639 | |
| KO | K00910 | |
| OMA | DHVQTHL | |
| OrthoDB | EOG7FV3PP | |
| PhylomeDB | Q09639 | |
| Reactome | REACT_242825 REACT_257432 | |
| SignaLink | Q09639 | |
| NextBio | 887266 | |
| Proteomes | UP000001940 | |
| GO | GO:0005524 GO:0004703 GO:0006935 GO:0006972 GO:0032501 GO:0042048 GO:0040010 GO:0007165 GO:0038032 | |
| Gene3D | 2.30.29.30 | |
| InterPro | IPR000961 IPR000239 IPR011009 IPR001849 IPR011993 IPR000719 IPR017441 IPR016137 IPR002290 IPR008271 | |
| Pfam | PF00069 PF00615 | |
| PRINTS | PR00717 | |
| SMART | SM00233 SM00315 SM00133 SM00220 | |
| SUPFAM | SSF48097 SSF56112 | |
| PROSITE | PS51285 PS50003 PS00107 PS50011 PS00108 PS50132 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:2001259 |
positive regulation of cation channel activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060160 |
negative regulation of dopamine receptor signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0040017 |
positive regulation of locomotion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042429 |
serotonin catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901046 |
positive regulation of oviposition |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1902074 |
response to salt |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050921 |
positive regulation of chemotaxis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042048 |
olfactory behavior |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
WB:WBVar00241640 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0040010 |
positive regulation of growth rate |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
WB:WBGene00000195 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032501 |
multicellular organismal process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
WB:WBGene00000195 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006972 |
hyperosmotic response |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
WB:WBVar00241640 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006935 |
chemotaxis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
WB:WBVar00241640 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004672 |
protein kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004703 |
G protein-coupled receptor kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000239 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000239 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004703 |
G protein-coupled receptor kinase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016301 |
kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016310 |
phosphorylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006935 |
chemotaxis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004674 |
protein serine/threonine kinase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Topalidou, I et al. (2017) Dopamine negatively modulates the NCA ion channels in C. elegans. PLoS Genet. 13 e1007032 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Wang, J et al. (2017) G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in . J. Biol. Chem. 292 5943-5956 PubMed GONUTS page
- ↑ 3.0 3.1 Hukema, RK et al. (2006) Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans. EMBO J. 25 312-22 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 Fukuto, HS et al. (2004) G protein-coupled receptor kinase function is essential for chemosensation in C. elegans. Neuron 42 581-93 PubMed GONUTS page
n
p
- Peloderinae
- GO:0016310 ! phosphorylation
- GO:0040017 ! positive regulation of locomotion
- GO:2001259 ! positive regulation of cation channel activity
- GO:1901046 ! positive regulation of egg-laying behavior
- GO:0040010 ! positive regulation of growth rate
- GO:0050921 ! positive regulation of chemotaxis
- GO:0004672 ! protein kinase activity
- GO:0006468 ! protein phosphorylation
- GO:0004674 ! protein serine/threonine kinase activity
