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CAEEL:GPDH2

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) gpdh-2
Protein Name(s) Probable glycerol-3-phosphate dehydrogenase 2
External Links
UniProt P34517
EMBL Z22180
PIR S40754
RefSeq NP_871632.1
UniGene Cel.10288
ProteinModelPortal P34517
SMR P34517
BioGrid 41593
IntAct P34517
MINT MINT-211360
STRING 6239.K11H3.1b
EPD P34517
PaxDb P34517
PeptideAtlas P34517
PRIDE P34517
EnsemblMetazoa K11H3.1b
GeneID 176399
CTD 176399
WormBase K11H3.1b
eggNOG KOG2711
COG0240
GeneTree ENSGT00390000003114
HOGENOM HOG000246855
InParanoid P34517
OMA NFCEATI
OrthoDB EOG091G0DO6
PhylomeDB P34517
Reactome [www.reactome.org/content/detail/R-CEL-1483166 R-CEL-1483166]
[www.reactome.org/content/detail/R-CEL-75109 R-CEL-75109]
PRO PR:P34517
Proteomes UP000001940
Bgee WBGene00010778
ExpressionAtlas P34517
GO GO:0009331
GO:0004367
GO:0004368
GO:0051287
GO:0005975
GO:0046168
GO:0006972
GO:0006973
Gene3D 1.10.1040.10
3.40.50.720
InterPro IPR008927
IPR013328
IPR006168
IPR006109
IPR017751
IPR011128
IPR016040
Pfam PF07479
PF01210
PIRSF PIRSF000114
PRINTS PR00077
SUPFAM SSF48179
SSF51735
TIGRFAMs TIGR03376
PROSITE PS00957

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004367

glycerol-3-phosphate dehydrogenase [NAD+] activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006109
InterPro:IPR006168
InterPro:IPR017751

F

Seeded From UniProt

GO:0004367

glycerol-3-phosphate dehydrogenase [NAD+] activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.1.1.8

F

Seeded From UniProt

GO:0004368

glycerol-3-phosphate dehydrogenase activity

PMID:10393177[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q00055

F

Seeded From UniProt

GO:0004368

glycerol-3-phosphate dehydrogenase activity

PMID:14644776[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q00055

F

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

Seeded From UniProt

GO:0005737

cytoplasm

GO_REF:0000039

IEA: Inferred from Electronic Annotation

UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006109

P

Seeded From UniProt

GO:0006072

glycerol-3-phosphate metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006168

P

Seeded From UniProt

GO:0006972

hyperosmotic response

PMID:10393177[1]

IGI: Inferred from Genetic Interaction

SGD:S000004103

P

Seeded From UniProt

GO:0006973

intracellular accumulation of glycerol

PMID:10393177[1]

IGI: Inferred from Genetic Interaction

SGD:S000004103

P

Seeded From UniProt

GO:0009331

glycerol-3-phosphate dehydrogenase complex

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006168

C

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013328

F

Seeded From UniProt

GO:0016491

oxidoreductase activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

F

Seeded From UniProt

GO:0016616

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011128

F

Seeded From UniProt

GO:0042803

protein homodimerization activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017751

F

Seeded From UniProt

GO:0046168

glycerol-3-phosphate catabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011128

P

Seeded From UniProt

GO:0051287

NAD binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011128
InterPro:IPR017751

F

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006109
InterPro:IPR006168
InterPro:IPR008927
InterPro:IPR011128
InterPro:IPR013328
InterPro:IPR017751

P

Seeded From UniProt

GO:0055114

oxidation-reduction process

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0560

P

Seeded From UniProt

GO:0047484

regulation of response to osmotic stress

PMID:28166192[3]

IMP: Inferred from Mutant Phenotype

P

Fig 2b shows that GPDH-2 is required for parental protection of progeny in response to osmotic stress (i.e. the parental protein is required to regulate response to progeny's osmotic stress). The protein is called GPDH-2 in the paper, used with the organism C. elegans

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Kawasaki, M et al. (1999) A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons. EMBO J. 18 3604-15 PubMed GONUTS page
  2. Lamitina, ST et al. (2004) Adaptation of the nematode Caenorhabditis elegans to extreme osmotic stress. Am. J. Physiol., Cell Physiol. 286 C785-91 PubMed GONUTS page
  3. Burton, NO et al. (2017) Insulin-like signalling to the maternal germline controls progeny response to osmotic stress. Nat. Cell Biol. PubMed GONUTS page