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CAEEL:GCY33

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) gcy-33
Protein Name(s) Soluble guanylate cyclase gcy-33
External Links
UniProt P90895
EMBL AY275181
Z75953
Z78012
PIR T20156
RefSeq NP_001256391.1
UniGene Cel.3261
ProteinModelPortal P90895
SMR P90895
PaxDb P90895
EnsemblMetazoa F57F5.2a
GeneID 179644
KEGG cel:CELE_F57F5.2
UCSC F57F5.2
CTD 179644
WormBase F57F5.2a
eggNOG COG2114
GeneTree ENSGT00760000118959
HOGENOM HOG000022481
InParanoid P90895
PhylomeDB P90895
NextBio 906276
Proteomes UP000001940
ExpressionAtlas P90895
GO GO:0005737
GO:0070027
GO:0005525
GO:0004383
GO:0020037
GO:0046872
GO:0070026
GO:0019826
GO:0035556
GO:0070482
Gene3D 3.30.70.1230
InterPro IPR001054
IPR018297
IPR011645
IPR011644
IPR024096
IPR029787
Pfam PF00211
PF07700
PF07701
SMART SM00044
SUPFAM SSF111126
SSF55073
PROSITE PS00452
PS50125

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0007635

chemosensory behavior

PMID:23874221[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0050913

sensory perception of bitter taste

PMID:23874221[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

has_input:(CHEBI:15854)

Seeded From UniProt

complete

involved_in

GO:0050913

sensory perception of bitter taste

PMID:23874221[1]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:O76360

P

has_input:(CHEBI:15854)

Seeded From UniProt

complete

involved_in

GO:0007635

chemosensory behavior

PMID:23874221[1]

ECO:0000316

genetic interaction evidence used in manual assertion

UniProtKB:O76360

P

Seeded From UniProt

complete

involved_in

GO:0070482

response to oxygen levels

PMID:19323996[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

WB:WBVar00091535

P

Seeded From UniProt

complete

enables

GO:0070027

carbon monoxide sensor activity

PMID:21491957[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0070026

nitric oxide binding

PMID:21491957[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0019826

oxygen sensor activity

PMID:19323996[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

WB:WBVar00091535

F

Seeded From UniProt

complete

enables

GO:0019826

oxygen sensor activity

PMID:21491957[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004383

guanylate cyclase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011645

F

Seeded From UniProt

complete

involved_in

GO:0006182

cGMP biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011645

P

Seeded From UniProt

complete

involved_in

GO:0009190

cyclic nucleotide biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001054
InterPro:IPR018297

P

Seeded From UniProt

complete

enables

GO:0016849

phosphorus-oxygen lyase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001054
InterPro:IPR018297

F

Seeded From UniProt

complete

enables

GO:0020037

heme binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011644
InterPro:IPR038158

F

Seeded From UniProt

complete

involved_in

GO:0035556

intracellular signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001054
InterPro:IPR018297

P

Seeded From UniProt

complete

enables

GO:0004383

guanylate cyclase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.6.1.2

F

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006182

cGMP biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0141

P

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Krzyzanowski, MC et al. (2013) The C. elegans cGMP-dependent protein kinase EGL-4 regulates nociceptive behavioral sensitivity. PLoS Genet. 9 e1003619 PubMed GONUTS page
  2. 2.0 2.1 Zimmer, M et al. (2009) Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases. Neuron 61 865-79 PubMed GONUTS page
  3. 3.0 3.1 3.2 Derbyshire, ER et al. (2011) Probing domain interactions in soluble guanylate cyclase. Biochemistry 50 4281-90 PubMed GONUTS page