CAEEL:G5EDP2

Species (Taxon ID)	Caenorhabditis elegans. (6239)
Gene Name(s)	No Information Provided.
Protein Name(s)	3-keto-acyl-CoA thiolase (ECO:0000313 with EMBL:BAA20377.1) Protein DAF-22 (ECO:0000313 with EMBL:CAA19548.1)
External Links
UniProt	G5EDP2
EMBL	D86473 AL023847
PIR	T27202
RefSeq	NP_496639.1
UniGene	Cel.6919
SMR	G5EDP2
IntAct	G5EDP2
EnsemblMetazoa	Y57A10C.6
GeneID	174881
KEGG	cel:CELE_Y57A10C.6
CTD	174881
WormBase	Y57A10C.6
GeneTree	ENSGT00530000062928
KO	K08764
OMA	SIIKMVG
PhylomeDB	G5EDP2
Reactome	REACT_197639 REACT_251105 REACT_252009
NextBio	885892
PRO	PR:G5EDP2
Proteomes	UP000001940
GO	GO:0005777 GO:0016747
Gene3D	3.40.47.10
InterPro	IPR002155 IPR016039 IPR016038 IPR020615 IPR020617 IPR020613 IPR020616
Pfam	PF02803 PF00108
PIRSF	PIRSF000429
SUPFAM	SSF53901
PROSITE	PS00098 PS00737

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0043053	dauer entry	PMID:19174521^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043054	dauer exit	PMID:19174521^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008355	olfactory learning	PMID:20929849^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048639	positive regulation of developmental growth	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061063	positive regulation of nematode larval development	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006637	acyl-CoA metabolic process	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(WBbt:0005772)	Seeded From UniProt	complete
involved_in	GO:0010888	negative regulation of lipid storage	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(WBbt:0005772)	Seeded From UniProt	complete
involved_in	GO:0000038	very long-chain fatty acid metabolic process	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(WBbt:0005772)	Seeded From UniProt	complete
enables	GO:0033814	propanoyl-CoA C-acyltransferase activity	PMID:9151950^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1904070	ascaroside biosynthetic process	PMID:19174521^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042811	pheromone biosynthetic process	PMID:19174521^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(WBbt:0005772)	Seeded From UniProt	complete
involved_in	GO:0042811	pheromone biosynthetic process	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050920	regulation of chemotaxis	PMID:20929849^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005777	peroxisome	PMID:20176933^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005777	peroxisome	PMID:19496754^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005777	peroxisome	PMID:19174521^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0019236	response to pheromone	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043053	dauer entry	PMID:19496754^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032385	positive regulation of intracellular cholesterol transport	PMID:21873635^[6]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001211927 UniProtKB:P07857 UniProtKB:P22307	P		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016039	F		Seeded From UniProt	complete
enables	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002155 InterPro:IPR020613 InterPro:IPR020615 InterPro:IPR020616 InterPro:IPR020617	F		Seeded From UniProt	complete
enables	GO:0033814	propanoyl-CoA C-acyltransferase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.3.1.176	F		Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0445	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
part_of	GO:0005777	peroxisome	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0576 UniProtKB-SubCell:SL-0204	C		Seeded From UniProt	complete
enables	GO:0008289	lipid binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0446	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Butcher, RA et al. (2009) Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc. Natl. Acad. Sci. U.S.A. 106 1875-9 PubMed GONUTS page
↑ ^2.0 ^2.1 Yamada, K et al. (2010) Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans. Science 329 1647-50 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Joo, HJ et al. (2009) Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis. Biochem. J. 422 61-71 PubMed GONUTS page
↑ Bun-Ya, M et al. (1997) A second isoform of 3-ketoacyl-CoA thiolase found in Caenorhabditis elegans, which is similar to sterol carrier protein x but lacks the sequence of sterol carrier protein 2. Eur. J. Biochem. 245 252-9 PubMed GONUTS page
↑ Zhang, SO et al. (2010) Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 107 4640-5 PubMed GONUTS page
↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19174521-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Butcher, RA et al. (2009) Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc. Natl. Acad. Sci. U.S.A. 106 1875-9 PubMed GONUTS page

[PMID:20929849-2] 2.0 ^2.1 Yamada, K et al. (2010) Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans. Science 329 1647-50 PubMed GONUTS page

[PMID:19496754-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Joo, HJ et al. (2009) Caenorhabditis elegans utilizes dauer pheromone biosynthesis to dispose of toxic peroxisomal fatty acids for cellular homoeostasis. Biochem. J. 422 61-71 PubMed GONUTS page

[PMID:9151950-4] Bun-Ya, M et al. (1997) A second isoform of 3-ketoacyl-CoA thiolase found in Caenorhabditis elegans, which is similar to sterol carrier protein x but lacks the sequence of sterol carrier protein 2. Eur. J. Biochem. 245 252-9 PubMed GONUTS page

[PMID:20176933-5] Zhang, SO et al. (2010) Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 107 4640-5 PubMed GONUTS page

[PMID:21873635-6] Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CAEEL:G5EDP2

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Notes

References

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