GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
BUNLC:D3K4J9
Contents
| Species (Taxon ID) | Bunyavirus La Crosse. (11577) | |
| Gene Name(s) | NSs (ECO:0000313 with EMBL:ADC41914.1) | |
| Protein Name(s) | Nonstructural protein (ECO:0000313 with EMBL:ADC41914.1) | |
| External Links | ||
| UniProt | D3K4J9 | |
| EMBL | GU371308 | |
| GO | GO:0016032 | |
| InterPro | IPR000797 | |
| Pfam | PF01104 | |
| PIRSF | PIRSF003954 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0046774 |
suppression by virus of host intracellular interferon activity |
ECO:0000315 |
P |
Figure 5B shows that when the nonstructural protein was expressed, the interferon induction system was suppressed, thus suppressing the innate immune system of the host. The function of the NSs is to suppress the innate immune system of the host and to allow the infection of the virus to take hold. |
complete | |||||
|
involved_in |
GO:0046774 |
suppression by virus of host intracellular interferon activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Blakqori, G et al. (2007) La Crosse bunyavirus nonstructural protein NSs serves to suppress the type I interferon system of mammalian hosts. J. Virol. 81 4991-9 PubMed GONUTS page
