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BRUA2:Q2YNH3
Contents
| Species (Taxon ID) | Brucella abortus (strain 2308). (359391) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Uncharacterized protein (ECO:0000313 with EMBL:CAJ10803.1) | |
| External Links | ||
| UniProt | Q2YNH3 | |
| EMBL | AM040264 | |
| RefSeq | WP_002963960.1 | |
| PRIDE | Q2YNH3 | |
| EnsemblBacteria | CAJ10803 KFJ46244 | |
| GeneID | 3787531 | |
| KEGG | bmf:BAB1_0847 | |
| PATRIC | 17844607 | |
| eggNOG | bactNOG81339 | |
| HOGENOM | HOG000289080 | |
| OMA | PQVADCV | |
| OrthoDB | EOG6XQ3Q3 | |
| BioCyc | BABO359391:GKDV-861-MONOMER BMEL359391:GJOQ-861-MONOMER | |
| Proteomes | UP000002719 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0044177 |
host cell Golgi apparatus |
ECO:0000314 |
C |
Figure 3. Confocal micrographs of HeLa cells transfected with Brucella abortus effector protein BspC expressing GFP displayed a golgi apparatus localization. Figure 4. Shows co-localization of BspC with a protein resident in golgi GM130 that confirmed BspC golgi localization. |
complete | |||||
| GO:0042000 |
translocation of peptides or proteins into host |
ECO:0000314 |
P |
Figure 1. TEM1 b-lactamase protein translocation reporter assay. Panel A and B shows percentage of shift in fluorescence emission that correlates with protein Brucella putative effector BAB1_0847 being translocated into J774A.1 host cell (murine cell line). Panel C and D shows representative fluorescence micrographs of protein translocation. Also look Figure S1 and S2. Figure 2. VirB-dependent translocation of Brucella BsP effectors into J774.A1 cells. Panel A. B. abortus strain 2308 (black bars) or virB9 mutant strain (white bars) expressing the CyaA fusions to the indicated Brucella effector proteins were used to infect J774.A1 cells, and the cAMP level of infected cells was determined. |
complete | |||||
| GO:0034976 |
response to endoplasmic reticulum stress |
ECO:0000314 |
P |
Figure S1. Panel B and C shows that, when ectopically expressed in mammalian cells (HEK 293T), BAB1_0847 expression induces significant ER stress to levels similar or higher than a positive control VceC and upregulation of BiP, but not CHOP. |
complete | |||||
Notes
bspC
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Myeni, S et al. (2013) Brucella modulates secretory trafficking via multiple type IV secretion effector proteins. PLoS Pathog. 9 e1003556 PubMed GONUTS page
