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BRUA2:4HYPE

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Species (Taxon ID) Brucella abortus (strain 2308). (359391)
Gene Name(s) prpA
Protein Name(s) 4-hydroxyproline epimerase

Hydroxyproline-2-epimerase HyPRE

External Links
UniProt Q2YLF3
EMBL AM040264
RefSeq WP_002964871.1
ProteinModelPortal Q2YLF3
EnsemblBacteria CAJ11756
GeneID 3788305
KEGG bmf:BAB1_1800
PATRIC 17846634
HOGENOM HOG000084336
KO K12658
OMA ARMAQWY
OrthoDB EOG6SNDV3
BioCyc BABO359391:GKDV-1844-MONOMER
BMEL359391:GJOQ-1844-MONOMER
Proteomes UP000002719
GO GO:0047580
GO:0042116
InterPro IPR008794
Pfam PF05544
PIRSF PIRSF029792

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0044068

modulation by symbiont of host cellular process

PMID:23720774[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Figure 1A shows treatment with increasing doses of PRPa results in increasing numbers of B-cells.

complete
CACAO 10422

enables

GO:0047580

4-hydroxyproline epimerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

F

Seeded From UniProt Experimental evidence for 4-hydroxyproline epimerase activity is available for 4HYPE from B. abortus (strain 544) in PMID:17849014[2].

complete

enables

GO:0016853

isomerase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Spera, JM et al. (2013) A Brucella virulence factor targets macrophages to trigger B-cell proliferation. J. Biol. Chem. 288 20208-16 PubMed GONUTS page
  2. Goytia, M et al. (2007) Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. PLoS One 2 e885 PubMed GONUTS page