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BPT4:TEV1

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Species (Taxon ID) Enterobacteria phage T4 (Bacteriophage T4). (10665)
Gene Name(s) ITEVIR
Protein Name(s) Intron-associated endonuclease 1

I-TevI IRF protein

External Links
UniProt P13299
EMBL M12742
AF158101
PIR T10130
RefSeq NP_049849.3
PDB 1I3J
1LN0
1MK0
1T2T
PDBsum 1I3J
1LN0
1MK0
1T2T
ProteinModelPortal P13299
SMR P13299
MoonProt P13299
REBASE 2625
GeneID 1258722
KEGG vg:1258722
EvolutionaryTrace P13299
Proteomes UP000009087
GO GO:0003677
GO:0004519
GO:0006314
Gene3D 3.40.1440.10
InterPro IPR027299
IPR000305
IPR006350
IPR003611
Pfam PF01541
PF07460
SMART SM00465
SM00496
SUPFAM SSF82771
TIGRFAMs TIGR01453
PROSITE PS50164

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:1990238

double-stranded DNA endodeoxyribonuclease activity

PMID:2543665[1]

ECO:0000314

F

Fig 3

complete
CACAO 12066

enables

GO:0008270

zinc ion binding

PMID:15361856[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0017053

transcriptional repressor complex

PMID:15361856[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:15361856[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0001217

DNA-binding transcription repressor activity

PMID:15361856[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

PMID:15361856[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

PMID:15361856[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0043565

sequence-specific DNA binding

PMID:15361856[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

PMID:2543665[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

PMID:2543665[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003611

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006350

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

involved_in

GO:0006314

intron homing

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0404

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 West, DK et al. (1989) Evidence that the intron open reading frame of the phage T4 td gene encodes a specific endonuclease. J. Biol. Chem. 264 10343-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Edgell, DR et al. (2004) Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor. Nat. Struct. Mol. Biol. 11 936-44 PubMed GONUTS page