GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
BPT4:DMA
Contents
Species (Taxon ID) | Enterobacteria phage T4 (Bacteriophage T4). (10665) | |
Gene Name(s) | DAM | |
Protein Name(s) | DNA adenine methylase
DNA-(N(6)-adenine)-methyltransferase (ECO:0000303 with PMID:12501249[1]) Deoxyadenosyl-methyltransferase M.EcoT4Dam | |
External Links | ||
UniProt | P04392 | |
EMBL | X01416 X17641 K03113 AF158101 | |
PIR | A00554 | |
RefSeq | NP_049647.1 | |
PDB | 1Q0S 1Q0T 1YF3 1YFJ 1YFL | |
PDBsum | 1Q0S 1Q0T 1YF3 1YFJ 1YFL | |
ProteinModelPortal | P04392 | |
SMR | P04392 | |
REBASE | 2837 | |
GeneID | 1258548 | |
KEGG | vg:1258548 | |
KO | K06223 | |
BRENDA | 2.1.1.72 | |
EvolutionaryTrace | P04392 | |
Proteomes | UP000009087 | |
GO | GO:0003676 GO:0009007 GO:0006260 GO:0016032 | |
Gene3D | 1.10.1020.10 3.40.50.150 | |
InterPro | IPR023095 IPR002052 IPR012263 IPR012327 IPR029063 | |
Pfam | PF02086 | |
PIRSF | PIRSF000398 | |
PRINTS | PR00505 | |
SUPFAM | SSF53335 | |
TIGRFAMs | TIGR00571 | |
PROSITE | PS00092 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0009008 |
DNA-methyltransferase activity |
ECO:0000314 |
F |
Bacteriophage T4 dam gene expressed in plasmid by direct assay by authors. Fig 6 |
complete | |||||
GO:0032259 |
methylation |
ECO:0000315 |
P |
Table 1 shows that the mutant phenotype of T4 with a different amino acid at residue 126 had higher methylation rates of different amino acids, due to relaxation in sequence specificity caused by the mutation. |
complete | |||||
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008168 |
methyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0009007 |
site-specific DNA-methyltransferase (adenine-specific) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032259 |
methylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032775 |
DNA methylation on adenine |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0009007 |
site-specific DNA-methyltransferase (adenine-specific) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032259 |
methylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0099018 |
restriction-modification system evasion by virus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008168 |
methyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zinoviev, VV et al. (2003) Bacteriophage T4 Dam DNA-(N6-adenine)-methyltransferase. Processivity and orientation to the methylation target. J. Biol. Chem. 278 7829-33 PubMed GONUTS page
- ↑ Kossykh, VG et al. (1995) Phage T4 DNA [N6-adenine]methyltransferase. Overexpression, purification, and characterization. J. Biol. Chem. 270 14389-93 PubMed GONUTS page
- ↑ Miner, Z et al. (1989) Single amino acid changes that alter the DNA sequence specificity of the DNA-[N6-adenine] methyltransferase (Dam) of bacteriophage T4. Nucleic Acids Res. 17 8149-57 PubMed GONUTS page