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BOVIN:TY3H

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) TH
Protein Name(s) Tyrosine 3-monooxygenase

Tyrosine 3-hydroxylase TH

External Links
UniProt P17289
EMBL M36794
M36705
PIR I45983
JL0039
RefSeq NP_776309.1
UniGene Bt.64937
ProteinModelPortal P17289
SMR P17289
STRING 9913.ENSBTAP00000038050
BindingDB P17289
ChEMBL CHEMBL3713
PRIDE P17289
GeneID 280707
KEGG bta:280707
CTD 7054
eggNOG COG3186
HOGENOM HOG000233373
HOVERGEN HBG006841
InParanoid P17289
KO K00501
SABIO-RK P17289
UniPathway UPA00747
NextBio 20804888
Proteomes UP000009136
GO GO:0005506
GO:0004511
GO:0009072
GO:0042416
GO:0042136
Gene3D 1.10.800.10
InterPro IPR001273
IPR019774
IPR005962
IPR019773
IPR021164
PANTHER PTHR11473
Pfam PF00351
PF12549
PIRSF PIRSF000336
PRINTS PR00372
SUPFAM SSF56534
TIGRFAMs TIGR01269
PROSITE PS51410

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045471

response to ethanol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000158541
RGD:3853
UniProtKB:P07101

P

Seeded From UniProt

complete

part_of

GO:0043204

perikaryon

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98735
PANTHER:PTN000158532
RGD:3853

C

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98735
PANTHER:PTN000158532
RGD:3853
WB:WBGene00000296

C

Seeded From UniProt

complete

involved_in

GO:0007507

heart development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98735
PANTHER:PTN000158541
RGD:3853

P

Seeded From UniProt

complete

involved_in

GO:0006585

dopamine biosynthetic process from tyrosine

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98735
PANTHER:PTN001690342
RGD:3853

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98735
PANTHER:PTN000158532
RGD:3853
UniProtKB:P07101
UniProtKB:Q9PU40

C

Seeded From UniProt

complete

enables

GO:0004511

tyrosine 3-monooxygenase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000158532
RGD:3853
UniProtKB:P07101
UniProtKB:Q9PU40
WB:WBGene00000296
ZFIN:ZDB-GENE-990621-5

F

Seeded From UniProt

complete

involved_in

GO:0001666

response to hypoxia

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000158541
RGD:3853
UniProtKB:P07101

P

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001273
InterPro:IPR036951

F

Seeded From UniProt

complete

enables

GO:0004511

tyrosine 3-monooxygenase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005962
InterPro:IPR021164

F

Seeded From UniProt

complete

enables

GO:0005506

iron ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001273
InterPro:IPR036951

F

Seeded From UniProt

complete

involved_in

GO:0009072

aromatic amino acid family metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001273
InterPro:IPR036951

P

Seeded From UniProt

complete

enables

GO:0016714

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR019773
InterPro:IPR019774

F

Seeded From UniProt

complete

involved_in

GO:0042423

catecholamine biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005962

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001273
InterPro:IPR005962
InterPro:IPR019773
InterPro:IPR019774
InterPro:IPR021164
InterPro:IPR036951

P

Seeded From UniProt

complete

enables

GO:0004511

tyrosine 3-monooxygenase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.16.2

F

Seeded From UniProt

complete

enables

GO:0004497

monooxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0503

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

involved_in

GO:0042423

catecholamine biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0127

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0042136

neurotransmitter biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0530

P

Seeded From UniProt

complete

involved_in

GO:0042416

dopamine biosynthetic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00747

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page