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BOVIN:RAC1

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) RAC1
Protein Name(s) Ras-related C3 botulinum toxin substrate 1

p21-Rac1

External Links
UniProt P62998
EMBL AF175262
BC103061
RefSeq NP_776588.1
UniGene Bt.106827
ProteinModelPortal P62998
SMR P62998
IntAct P62998
STRING 9913.ENSBTAP00000012170
BindingDB P62998
PaxDb P62998
PRIDE P62998
GeneID 281440
KEGG bta:281440
CTD 5879
eggNOG KOG0393
COG1100
HOGENOM HOG000233974
HOVERGEN HBG009351
InParanoid P62998
KO K04392
NextBio 20805425
Proteomes UP000009136
GO GO:0005829
GO:0042470
GO:0016020
GO:0005886
GO:0005525
GO:0051022
GO:0048870
GO:0001934
GO:0030334
GO:0071526
GO:0007264
Gene3D 3.40.50.300
InterPro IPR027417
IPR005225
IPR001806
IPR003578
Pfam PF00071
SMART SM00174
SUPFAM SSF52540
TIGRFAMs TIGR00231
PROSITE PS51420

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0030027

lamellipodium

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P63001

C

Seeded From UniProt

complete

involved_in

GO:0001764

neuron migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P63001

P

Seeded From UniProt

complete

involved_in

GO:0071526

semaphorin-plexin signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6RUV5

P

Seeded From UniProt

complete

enables

GO:0051022

Rho GDP-dissociation inhibitor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6RUV5

F

Seeded From UniProt

complete

involved_in

GO:0048870

cell motility

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P63000

P

Seeded From UniProt

complete

involved_in

GO:0030334

regulation of cell migration

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P63000

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6RUV5

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q6RUV5

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P63000

F

Seeded From UniProt

complete

involved_in

GO:0001934

positive regulation of protein phosphorylation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P63000

P

Seeded From UniProt

complete

involved_in

GO:1902622

regulation of neutrophil migration

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97845
MGI:MGI:97846
PANTHER:PTN002374567
UniProtKB:P15153
UniProtKB:P63000
ZFIN:ZDB-GENE-040625-27

P

Seeded From UniProt

complete

part_of

GO:0043197

dendritic spine

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000633314
RGD:619755
UniProtKB:P63000

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
MGI:MGI:97845
PANTHER:PTN002784637
RGD:619755
UniProtKB:P15153
UniProtKB:P63000
WB:WBGene00004287

C

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97845
PANTHER:PTN002784637
RGD:619755
UniProtKB:P63000
WB:WBGene00000424
dictyBase:DDB_G0293526

C

Seeded From UniProt

complete

involved_in

GO:0030036

actin cytoskeleton organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
FB:FBgn0014011
MGI:MGI:97845
MGI:MGI:97846
PANTHER:PTN002784637
RGD:1307568
RGD:619755
UniProtKB:P15153
UniProtKB:P63000
UniProtKB:Q6LC82
WB:WBGene00004287

P

Seeded From UniProt

complete

involved_in

GO:0030031

cell projection assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97846
PANTHER:PTN002374567

P

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
FB:FBgn0014011
PANTHER:PTN002784637
RGD:619755
UniProtKB:P63000
dictyBase:DDB_G0293526

F

Seeded From UniProt

complete

involved_in

GO:0016601

Rac protein signal transduction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002374567
RGD:619755

P

Seeded From UniProt

complete

involved_in

GO:0016477

cell migration

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
FB:FBgn0014011
MGI:MGI:97845
PANTHER:PTN002784637
RGD:619755
UniProtKB:Q6LC82
WB:WBGene00000424
WB:WBGene00004287
ZFIN:ZDB-GENE-030131-5415
ZFIN:ZDB-GENE-040625-27
dictyBase:DDB_G0293526

P

Seeded From UniProt

complete

involved_in

GO:0008045

motor neuron axon guidance

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
PANTHER:PTN002784640
WB:WBGene00000424
WB:WBGene00004287

P

Seeded From UniProt

complete

involved_in

GO:0007266

Rho protein signal transduction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010341
FB:FBgn0014011
MGI:MGI:1931551
PANTHER:PTN000632671
RGD:619921
UniProtKB:I3LVS7
UniProtKB:P61586
UniProtKB:P84095

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
MGI:MGI:97845
PANTHER:PTN002784637
UniProtKB:P63000
WB:WBGene00000424
WB:WBGene00004287

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
MGI:MGI:97845
MGI:MGI:97846
PANTHER:PTN002784637
RGD:619755
UniProtKB:P15153
UniProtKB:P63000
WB:WBGene00000424
ZFIN:ZDB-GENE-040625-27
dictyBase:DDB_G0280975
dictyBase:DDB_G0293526

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0039140
MGI:MGI:108446
MGI:MGI:97845
PANTHER:PTN000632671
RGD:619755
RGD:619921
RGD:71043
SGD:S000001380
TAIR:locus:2131606
TAIR:locus:2204380
UniProtKB:A0A1D8PDV5
UniProtKB:P15153
UniProtKB:P60953
UniProtKB:P61586
UniProtKB:P63000
UniProtKB:Q15669
UniProtKB:Q9SSX0
WB:WBGene00000390
WB:WBGene00000424
WB:WBGene00004287
WB:WBGene00004357

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010333
FB:FBgn0010341
FB:FBgn0014011
FB:FBgn0014020
MGI:MGI:106211
MGI:MGI:1096342
MGI:MGI:1916831
MGI:MGI:97845
MGI:MGI:97846
PANTHER:PTN000632671
PomBase:SPAC110.03
PomBase:SPAC16.01
PomBase:SPAC16A10.04
PomBase:SPAC1F7.04
PomBase:SPAC23C4.08
RGD:619755
RGD:619921
SGD:S000000046
SGD:S000001380
SGD:S000001763
SGD:S000004219
SGD:S000005034
SGD:S000005124
SGD:S000006369
TAIR:locus:2099232
TAIR:locus:2131606
UniProtKB:A0A1D8PCX9
UniProtKB:A0A1D8PH96
UniProtKB:P17081
UniProtKB:P60763
UniProtKB:P60953
UniProtKB:P61586
UniProtKB:P63000
UniProtKB:P84095
UniProtKB:Q5A904
WB:WBGene00000390
WB:WBGene00000424
WB:WBGene00003239
WB:WBGene00004287
WB:WBGene00004357

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001806
InterPro:IPR003578
InterPro:IPR005225

F

Seeded From UniProt

complete

involved_in

GO:0007264

small GTPase mediated signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003578

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

part_of

GO:0042470

melanosome

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0161

C

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0291

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page