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BOVIN:Q2KJE7

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) No Information Provided.
Protein Name(s) Proteasome (Prosome, macropain) activator subunit 1 (PA28 alpha) (ECO:0000313 with EMBL:AAI05380.1)

Proteasome activator complex subunit 1 (ECO:0000313 with Ensembl:ENSBTAP00000028520)

External Links
UniProt Q2KJE7
EMBL DAAA02028032
BC105379
RefSeq NP_001019680.2
UniGene Bt.52452
SMR Q2KJE7
Ensembl ENSBTAT00000028520
GeneID 510041
KEGG bta:510041
CTD 5720
GeneTree ENSGT00510000046374
HOVERGEN HBG053745
KO K06696
OMA TQISKYY
OrthoDB EOG7GTT4C
TreeFam TF106236
Reactome REACT_203739
REACT_203965
REACT_205339
REACT_205897
REACT_206368
REACT_207857
REACT_208116
REACT_208851
REACT_208889
REACT_211738
REACT_212887
REACT_213030
REACT_215163
REACT_217860
REACT_218058
REACT_222557
REACT_222622
REACT_223494
REACT_224434
REACT_225648
REACT_226120
REACT_227515
REACT_237530
REACT_252463
REACT_259250
REACT_269173
REACT_269531
REACT_271133
NextBio 20869251
Proteomes UP000009136
GO GO:0070062
GO:0008537
GO:0061133
GO:0019884
Gene3D 1.20.120.180
1.20.5.120
InterPro IPR009077
IPR003186
IPR003185
PANTHER PTHR10660
Pfam PF02251
PF02252
SUPFAM SSF47216

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0010950

positive regulation of endopeptidase activity

PMID:1587832[1]

ECO:0000314

P

Table 2; data corresponding to 20s proteasome's peptidase activity in the presence and in the absence of PA28. Fig.7 and Fig.8; visual representation of table 2 Peptidase activity increases in the presence of PA28

complete
CACAO 7686

involved_in

GO:0010950

positive regulation of endopeptidase activity

PMID:1587832[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000045

regulation of G1/S transition of mitotic cell cycle

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029133
PANTHER:PTN000069920

P

Seeded From UniProt

complete

involved_in

GO:0061136

regulation of proteasomal protein catabolic process

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029133
PANTHER:PTN000069920
UniProtKB:P61289

P

Seeded From UniProt

complete

enables

GO:0061133

endopeptidase activator activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029133
MGI:MGI:1096365
MGI:MGI:1096367
PANTHER:PTN000069920
UniProtKB:P61289

F

Seeded From UniProt

complete

involved_in

GO:0010950

positive regulation of endopeptidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000069920
UniProtKB:Q2KJE7

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0029133
PANTHER:PTN000069920

C

Seeded From UniProt

complete

part_of

GO:0005654

nucleoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000069920
UniProtKB:P61289

C

Seeded From UniProt

complete

enables

GO:0061133

endopeptidase activator activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P97371
ensembl:ENSMUSP00000134735

F

Seeded From UniProt

complete

involved_in

GO:0019884

antigen processing and presentation of exogenous antigen

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P97371
ensembl:ENSMUSP00000134735

P

Seeded From UniProt

complete

part_of

GO:0008537

proteasome activator complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003185
InterPro:IPR003186
InterPro:IPR009077
InterPro:IPR036252
InterPro:IPR036996
InterPro:IPR036997

C

Seeded From UniProt

complete

part_of

GO:0000502

proteasome complex

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0647

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ma, CP et al. (1992) Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain). J. Biol. Chem. 267 10515-23 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page