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BOVIN:LALBA

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) LALBA (synonyms: ALACTA)
Protein Name(s) Alpha-lactalbumin

Lactose synthase B protein

External Links
UniProt P00711
EMBL X06366
M18780
J05147
AB052163
AB052164
AB052165
AB052166
AB052167
AF249896
BT025469
BC102173
M90645
PIR A27360
RefSeq NP_776803.1
UniGene Bt.87412
PDB 1F6R
1F6S
1HFZ
2G4N
PDBsum 1F6R
1F6S
1HFZ
2G4N
ProteinModelPortal P00711
SMR P00711
BioGrid 159201
IntAct P00711
MINT MINT-1487560
Allergome 163
3165
PaxDb P00711
PRIDE P00711
Ensembl ENSBTAT00000007701
GeneID 281894
KEGG bta:281894
CTD 3906
eggNOG NOG72593
GeneTree ENSGT00550000074398
HOGENOM HOG000037357
HOVERGEN HBG052297
InParanoid P00711
KO K00704
OMA LAHKPLC
OrthoDB EOG7BW0M5
TreeFam TF324882
EvolutionaryTrace P00711
NextBio 20805791
Proteomes UP000009136
GO GO:0005576
GO:0005509
GO:0042802
GO:0004461
GO:0005989
InterPro IPR001916
IPR019799
IPR000545
IPR023346
PANTHER PTHR11407:SF5
Pfam PF00062
PRINTS PR00136
PR00135
SMART SM00263
SUPFAM SSF53955
PROSITE PS00128
PS51348

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0032355

response to estradiol

PMID:3585228[1]

ECO:0000314

direct assay evidence used in manual assertion

P

  • occurs_in:(UBERON:0001911)
  • happens_during:(GO:0007595)

Seeded From UniProt

complete

involved_in

GO:0032570

response to progesterone

PMID:3585228[1]

ECO:0000314

direct assay evidence used in manual assertion

P

  • occurs_in:(UBERON:0001911)
  • happens_during:(GO:0007595)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:9112130[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1903496

response to 11-deoxycorticosterone

PMID:3585228[1]

ECO:0000314

direct assay evidence used in manual assertion

P

  • happens_during:(GO:0007595)
  • occurs_in:(UBERON:0001911)

Seeded From UniProt

complete

involved_in

GO:1903494

response to dehydroepiandrosterone

PMID:3585228[1]

ECO:0000314

direct assay evidence used in manual assertion

P

  • happens_during:(GO:0007595)
  • occurs_in:(UBERON:0001911)

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:3585228[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0050830

defense response to Gram-positive bacterium

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96897
MGI:MGI:96902
PANTHER:PTN000892307
RGD:3026
UniProtKB:P61626

P

Seeded From UniProt

complete

involved_in

GO:0050829

defense response to Gram-negative bacterium

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:96897
MGI:MGI:96902
PANTHER:PTN000892307
RGD:1308401
RGD:3026

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:23416304[4]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P00711

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:23353684[5]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:P00711

F

Seeded From UniProt

complete

enables

GO:0004461

lactose synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000545

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000545

F

Seeded From UniProt

complete

involved_in

GO:0005989

lactose biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000545

P

Seeded From UniProt

complete

involved_in

GO:0005989

lactose biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0422

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Shamay, A et al. (1987) Inhibition of casein and fat synthesis and alpha-lactalbumin secretion by progesterone in explants from bovine lactating mammary glands. J. Endocrinol. 113 81-8 PubMed GONUTS page
  2. Keys, JE et al. (1997) Bovine mammary explant versus primary cell cultures: effect of bovine somatotropin and insulin-like growth factor-I on DNA content and protein synthesis. In Vitro Cell. Dev. Biol. Anim. 33 206-11 PubMed GONUTS page
  3. 3.0 3.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  4. Babenko, V & Dzwolak, W (2013) Amino acid sequence determinants in self-assembly of insulin chiral amyloid superstructures: role of C-terminus of B-chain in association of fibrils. FEBS Lett. 587 625-30 PubMed GONUTS page
  5. Wyatt, AR et al. (2013) Protease-activated alpha-2-macroglobulin can inhibit amyloid formation via two distinct mechanisms. FEBS Lett. 587 398-403 PubMed GONUTS page