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BOVIN:GALT1
Contents
| Species (Taxon ID) | Bos taurus (Bovine). (9913) | |
| Gene Name(s) | GALNT1 | |
| Protein Name(s) | Polypeptide N-acetylgalactosaminyltransferase 1
Polypeptide GalNAc transferase 1 GalNAc-T1 pp-GaNTase 1 Protein-UDP acetylgalactosaminyltransferase 1 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 Polypeptide N-acetylgalactosaminyltransferase 1 soluble form | |
| External Links | ||
| UniProt | Q07537 | |
| EMBL | L07780 L17437 | |
| PIR | A45987 | |
| RefSeq | NP_803485.1 | |
| UniGene | Bt.65693 | |
| ProteinModelPortal | Q07537 | |
| SMR | Q07537 | |
| STRING | 9913.ENSBTAP00000014882 | |
| CAZy | CBM13 GT27 | |
| PRIDE | Q07537 | |
| Ensembl | ENSBTAT00000014882 | |
| GeneID | 282241 | |
| KEGG | bta:282241 | |
| CTD | 2589 | |
| eggNOG | NOG239675 | |
| GeneTree | ENSGT00760000118828 | |
| HOGENOM | HOG000038227 | |
| HOVERGEN | HBG051699 | |
| InParanoid | Q07537 | |
| KO | K00710 | |
| OMA | IKHDRKT | |
| OrthoDB | EOG7J9VP2 | |
| TreeFam | TF313267 | |
| BRENDA | 2.4.1.41 | |
| Reactome | REACT_208023 | |
| UniPathway | UPA00378 | |
| NextBio | 20806060 | |
| Proteomes | UP000009136 | |
| GO | GO:0005576 GO:0032580 GO:0016021 GO:0048471 GO:0030246 GO:0030145 GO:0004653 GO:0006493 GO:0018242 GO:0018243 | |
| Gene3D | 3.90.550.10 | |
| InterPro | IPR001173 IPR029044 IPR000772 | |
| Pfam | PF00535 PF00652 | |
| SMART | SM00458 | |
| SUPFAM | SSF50370 SSF53448 | |
| PROSITE | PS50231 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000314 |
F |
Table 2 is a list of Km values determined from an kinetics experiment, the purified wild-type is the first entry in table, and all mutant proteins are normalized to wild-type activity. The glycoproteins formed were separated later with anion-exchanged chromatography. |
complete | |||||
|
enables |
GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006493 |
protein O-linked glycosylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030145 |
manganese ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006493 |
protein O-linked glycosylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0027558 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006493 |
protein O-linked glycosylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08912 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08912 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030145 |
manganese ion binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0018243 |
protein O-linked glycosylation via threonine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0018242 |
protein O-linked glycosylation via serine |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006493 |
protein O-linked glycosylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q10472 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004653 |
polypeptide N-acetylgalactosaminyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030246 |
carbohydrate binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032580 |
Golgi cisterna membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006486 |
protein glycosylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00378 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Wragg, S et al. (1997) Identification of essential histidine residues in UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-T1. Biochem. J. 328 ( Pt 1) 193-7 PubMed GONUTS page
- ↑ 2.0 2.1 Perrine, CL et al. (2009) Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2. J. Biol. Chem. 284 20387-97 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Elhammer, A & Kornfeld, S (1986) Purification and characterization of UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase from bovine colostrum and murine lymphoma BW5147 cells. J. Biol. Chem. 261 5249-55 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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- Pecora
- GO:0048471 ! perinuclear region of cytoplasm
- GO:0004653 ! polypeptide N-acetylgalactosaminyltransferase activity
- GO:0006486 ! protein glycosylation
- GO:0018243 ! protein O-linked glycosylation via threonine
- GO:0018242 ! protein O-linked glycosylation via serine
- GO:0006493 ! protein O-linked glycosylation
