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BOVIN:CO1A1

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Species (Taxon ID) Bos taurus (Bovine). (9913)
Gene Name(s) COL1A1
Protein Name(s) Collagen alpha-1(I) chain

Alpha-1 type I collagen

External Links
UniProt P02453
EMBL BC105184
PIR A91193
RefSeq NP_001029211.1
UniGene Bt.23316
ProteinModelPortal P02453
IntAct P02453
PaxDb P02453
PRIDE P02453
Ensembl ENSBTAT00000017420
GeneID 282187
KEGG bta:282187
CTD 1277
eggNOG NOG12793
GeneTree ENSGT00770000120467
HOGENOM HOG000085654
HOVERGEN HBG004933
InParanoid P02453
KO K06236
OMA KNCPGAQ
OrthoDB EOG7TJ3HH
TreeFam TF344135
Reactome REACT_204848
REACT_207047
REACT_208597
REACT_209041
REACT_215758
REACT_215983
REACT_219098
REACT_219927
REACT_220688
REACT_222217
REACT_222620
REACT_223425
REACT_224259
REACT_226104
NextBio 20806015
PMAP-CutDB P02453
Proteomes UP000009136
ExpressionAtlas P02453
GO GO:0005584
GO:0005737
GO:0005615
GO:0005201
GO:0046872
GO:0001568
GO:0060346
GO:0060351
GO:0071230
GO:0071260
GO:0032964
GO:0030199
GO:0048706
GO:0001958
GO:0060325
GO:0001957
GO:0010812
GO:0001649
GO:0090263
GO:0030335
GO:0010718
GO:0045893
GO:0070208
GO:0034504
GO:0015031
GO:0007605
GO:0043589
GO:0034505
GO:0007601
InterPro IPR008160
IPR000885
IPR001007
Pfam PF01410
PF01391
PF00093
ProDom PD002078
SMART SM00038
SM00214
PROSITE PS51461
PS01208
PS50184

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0032302

MutSbeta complex

PMID:P02453

ECO:0000255

C

Fig 5 shows PCR products after the protein was affected by the mutated allele

Missing: with/from
CACAO 5098

involved_in

GO:0043588

skin development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88467
PANTHER:PTN002771192

P

Seeded From UniProt

complete

involved_in

GO:0038063

collagen-activated tyrosine kinase receptor signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002771192
RGD:61817

P

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88445
MGI:MGI:88446
MGI:MGI:88452
MGI:MGI:88453
MGI:MGI:88457
MGI:MGI:88467
PANTHER:PTN002513067

C

Seeded From UniProt

complete

involved_in

GO:0030198

extracellular matrix organization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1095415
MGI:MGI:2152695
MGI:MGI:2672118
MGI:MGI:88451
PANTHER:PTN002513067
WB:WBGene00001263
ZFIN:ZDB-GENE-030131-2281

P

Seeded From UniProt

complete

involved_in

GO:0009612

response to mechanical stimulus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002771192
RGD:61817

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88467
PANTHER:PTN002771192
ZFIN:ZDB-GENE-030131-9102

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88452
MGI:MGI:88468
PANTHER:PTN002513067
RGD:61817
RGD:70936
RGD:727898
UniProtKB:P02452
UniProtKB:P02458
UniProtKB:P02461
UniProtKB:P08123
UniProtKB:Q9BXS0

C

Seeded From UniProt

complete

part_of

GO:0005584

collagen type I trimer

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88467
PANTHER:PTN002771192
UniProtKB:P02452

C

Seeded From UniProt

complete

enables

GO:0005201

extracellular matrix structural constituent

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104687
MGI:MGI:2672118
MGI:MGI:88457
MGI:MGI:88467
PANTHER:PTN002513067
UniProtKB:P02461
UniProtKB:P02462
UniProtKB:P53420

F

Seeded From UniProt

complete

involved_in

GO:0001568

blood vessel development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88467
PANTHER:PTN002771192
UniProtKB:P02452

P

Seeded From UniProt

complete

involved_in

GO:0001503

ossification

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002771192
RGD:61817

P

Seeded From UniProt

complete

involved_in

GO:0001501

skeletal system development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:88467
PANTHER:PTN002771192
UniProtKB:P02452
ZFIN:ZDB-GENE-030131-9102

P

Seeded From UniProt

complete

involved_in

GO:0090263

positive regulation of canonical Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0048706

embryonic skeletal system development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

enables

GO:0048407

platelet-derived growth factor binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

F

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0043589

skin morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

F

Seeded From UniProt

complete

involved_in

GO:0034505

tooth mineralization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0034504

protein localization to nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0032964

collagen biosynthetic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0030335

positive regulation of cell migration

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0030199

collagen fibril organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0010718

positive regulation of epithelial to mesenchymal transition

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0007605

sensory perception of sound

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0007601

visual perception

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

C

Seeded From UniProt

complete

part_of

GO:0005584

collagen type I trimer

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

C

Seeded From UniProt

complete

enables

GO:0002020

protease binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

F

Seeded From UniProt

complete

involved_in

GO:0001568

blood vessel development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0001501

skeletal system development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02452
ensembl:ENSP00000225964

P

Seeded From UniProt

complete

involved_in

GO:0071260

cellular response to mechanical stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0071230

cellular response to amino acid stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0070208

protein heterotrimerization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0060351

cartilage development involved in endochondral bone morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0060346

bone trabecula formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0060325

face morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0048705

skeletal system morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0043588

skin development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0010812

negative regulation of cell-substrate adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

C

Seeded From UniProt

complete

part_of

GO:0005584

collagen type I trimer

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

C

Seeded From UniProt

complete

part_of

GO:0005581

collagen trimer

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

C

Seeded From UniProt

complete

enables

GO:0005201

extracellular matrix structural constituent

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

F

Seeded From UniProt

complete

involved_in

GO:0001958

endochondral ossification

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0001957

intramembranous ossification

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0001649

osteoblast differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0001568

blood vessel development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

involved_in

GO:0001501

skeletal system development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P11087
ensembl:ENSMUSP00000001547

P

Seeded From UniProt

complete

enables

GO:0005201

extracellular matrix structural constituent

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000885

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005581

collagen trimer

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0176

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page