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BOTJA:VM3B

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Species (Taxon ID) Bothrops jararaca (Jararaca) (Bothrops jajaraca). (8724)
Gene Name(s) No Information Provided.
Protein Name(s) Zinc metalloproteinase-disintegrin-like botrocetin

Snake venom metalloproteinase SVMP von Willebrand factor-dependent platelet coagglutinin Disintegrin-like botrocetin

External Links
UniProt P22028
GO GO:0005576
GO:0016787
GO:0046872
GO:0035893

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0035893

negative regulation of platelet aggregation in other organism

PMID:15665869[1]

ECO:0000314

P

A higher percentage of platelets are activated when exposed to botrocetin than when not (Figure 5). This chemical introduced by Gaboon Vipers causes hemorrhaging.

complete
CACAO 6555

involved_in

GO:0035893

negative regulation of platelet aggregation in other organism

PMID:15665869[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Fukuda, K et al. (2005) The snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregation. Nat. Struct. Mol. Biol. 12 152-9 PubMed GONUTS page