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BACSU:TRMFO
Contents
| Species (Taxon ID) | Bacillus subtilis (strain 168). (224308) | |
| Gene Name(s) | trmFO (synonyms: gid, ylyC) | |
| Protein Name(s) | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
Folate-dependent tRNA (uracil-5-)-methyltransferase Folate-dependent tRNA(M-5-U54)-methyltransferase | |
| External Links | ||
| UniProt | P39815 | |
| EMBL | AJ000975 AL009126 L27797 U13634 | |
| PIR | A69632 | |
| RefSeq | NP_389495.1 | |
| ProteinModelPortal | P39815 | |
| SMR | P39815 | |
| STRING | 224308.BSU16130 | |
| PaxDb | P39815 | |
| EnsemblBacteria | CAB13486 | |
| GeneID | 938816 | |
| KEGG | bsu:BSU16130 | |
| PATRIC | 18975031 | |
| GenoList | BSU16130 | |
| eggNOG | COG1206 | |
| HOGENOM | HOG000252054 | |
| InParanoid | P39815 | |
| KO | K04094 | |
| OMA | RFGPMKP | |
| OrthoDB | EOG6J74VT | |
| PhylomeDB | P39815 | |
| BioCyc | BSUB:BSU16130-MONOMER | |
| Proteomes | UP000001570 | |
| GO | GO:0005737 GO:0030698 GO:0050660 GO:0047151 | |
| HAMAP | MF_01037 | |
| InterPro | IPR004417 IPR002218 IPR020595 | |
| Pfam | PF01134 | |
| TIGRFAMs | TIGR00137 | |
| PROSITE | PS01281 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008168 |
methyltransferase activity |
ECO:0000315 |
F |
Figure 2A and B indicate that the wild type cell extract was able to catalyze formation of m^5U-54 in vitro, however the mutant strain lacking the functional Gid protein was unable to catalyze such a methylation reaction. Thus this indicates that the gid gene product is involved in product of m^5Y-54 in tRNA. |
complete | |||||
| GO:0008168 |
methyltransferase activity |
ECO:0000314 |
F |
Figure 4 indicates the purified Gid protein catalyzes the site-specific formation of m5U-54 in [32P]-labeled yeast tRNAAsp transcript. |
complete | |||||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10375 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030488 |
tRNA methylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10375 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10375 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002098 |
tRNA wobble uridine modification |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10375 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008033 |
tRNA processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0047151 |
methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0047151 |
methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030698 |
5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100529 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100529 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100529 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008033 |
tRNA processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100529 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008168 |
methyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008033 |
tRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032259 |
methylation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Urbonavicius, J et al. (2005) Identification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria--evolutionary implications. Nucleic Acids Res. 33 3955-64 PubMed GONUTS page
- ↑ Ny, T et al. (1988) Purification of transfer RNA (m5U54)-methyltransferase from Escherichia coli. Association with RNA. Eur. J. Biochem. 177 467-75 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
