BACSU:SFP

Species (Taxon ID)	Bacillus subtilis (strain 168). (224308)
Gene Name(s)	sfp (synonyms: lpa-8)
Protein Name(s)	4'-phosphopantetheinyl transferase sfp Surfactin synthase-activating enzyme
External Links
UniProt	P39135
EMBL	X63158 X65610 L17438 X70356 D50562 AL009126
PIR	S20463
PDB	1QR0 2GE0 2GE1 4MRT
PDBsum	1QR0 2GE0 2GE1 4MRT
ProteinModelPortal	P39135
SMR	P39135
GenoList	BSU03570
InParanoid	P39135
BioCyc	MetaCyc:MONOMER-13919
EvolutionaryTrace	P39135
Proteomes	UP000001570
GO	GO:0008897 GO:0000287 GO:0017000 GO:0006633 GO:0009059
Gene3D	3.90.470.20
InterPro	IPR008278 IPR004568
Pfam	PF01648
SUPFAM	SSF56214
TIGRFAMs	TIGR00556

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:1900192	positive regulation of single-species biofilm formation	PMID:21278284	ECO:0000315			P		Table 1, 2nd row	complete CACAO 10157
	GO:0009059	macromolecule biosynthetic process	PMID:11572999	ECO:0000315			P		Surfactants are known to be important for the erection of aerial hyphae in fungi and the streptomycetes, caused at least in part by their ability to lower the surface tension of water.. A mutant (sfp) lacking the phosphopantetheinyltransferase that activates the nonribosomal peptide synthetase that produces surfactin formed thick but completely flat pellicles (Fig. 4A). Similarly, sfp mutant colonies were flat and small, spreading very little on the agar surface (Fig. 4 B and C). Low-magnification microscopy revealed that these mutant colonies did form projecting columns, but these grew laterally and eventually fused with each other (Fig. 4C), leading to small colonies lacking aerial structures.	complete CACAO 2636
involved_in	GO:1900192	positive regulation of single-species biofilm formation	PMID:21278284	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019878	lysine biosynthetic process via aminoadipic acid		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000259224 PomBase:SPAC17C9.02c	P		Seeded From UniProt	complete
enables	GO:0008897	holo-[acyl-carrier-protein] synthase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG12221 PANTHER:PTN000259224 PomBase:SPAC17C9.02c SGD:S000003122 UniProtKB:Q4X1W0 UniProtKB:Q59N08 UniProtKB:Q9NRN7 dictyBase:DDB_G0285927	F		Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004568 InterPro:IPR008278 InterPro:IPR037143	F		Seeded From UniProt	complete
involved_in	GO:0006633	fatty acid biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004568	P		Seeded From UniProt	complete
enables	GO:0008897	holo-[acyl-carrier-protein] synthase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004568 InterPro:IPR008278 InterPro:IPR037143	F		Seeded From UniProt	complete
enables	GO:0008897	holo-[acyl-carrier-protein] synthase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.8.7	F		Seeded From UniProt	complete
involved_in	GO:0017000	antibiotic biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0045	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
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References

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